Detailed information NTG1028035

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: WHOZ_RS11255
• Genome accession: NZ_LT592146
• Coordinates: 1896513..1897739 (+)
• Length: 408 a.a.
• NCBI ID: WP_047918752.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO O
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1891513..1902739

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WHOZ_RS11230 (WHOO_02087C)	dksA	1892689..1893105 (-)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
WHOZ_RS11235 (WHOO_02088C)	proC	1893253..1894044 (-)	792	WP_003694504.1	pyrroline-5-carboxylate reductase	-
WHOZ_RS11240 (WHOO_02089C)	-	1894093..1894500 (-)	408	WP_003690202.1	hypothetical protein	-
WHOZ_RS11245 (WHOO_02090C)	-	1894500..1895186 (-)	687	WP_003699139.1	YggS family pyridoxal phosphate-dependent enzyme	-
WHOZ_RS11250 (WHOO_02091)	pilT	1895306..1896349 (+)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
WHOZ_RS11255 (WHOO_02092)	pilU	1896513..1897739 (+)	1227	WP_047918752.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
WHOZ_RS11260 (WHOO_02093)	yccS	1897856..1900006 (+)	2151	WP_003699137.1	YccS family putative transporter	-
WHOZ_RS11270 (WHOO_02094C)	-	1900632..1900916 (-)	285	WP_003692093.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45642.26 Da
• Isoelectric Point: 7.3203

>NTDB_id=1028035 WHOZ_RS11255 WP_047918752.1 1896513..1897739(+) (pilU) [Neisseria gonorrhoeae strain WHO O]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=1028035 WHOZ_RS11255 WP_047918752.1 1896513..1897739(+) (pilU) [Neisseria gonorrhoeae strain WHO O]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGATCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387