Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   AB4922_RS11220 Genome accession   NZ_CP162911
Coordinates   2190383..2191453 (-) Length   356 a.a.
NCBI ID   WP_368774526.1    Uniprot ID   A0AB39IUI2
Organism   Bacillus aerius strain KW1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2185383..2196453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4922_RS11170 (AB4922_11170) sipW 2185477..2186049 (-) 573 WP_017357979.1 signal peptidase I SipW -
  AB4922_RS11175 (AB4922_11175) tapA 2186099..2186626 (-) 528 WP_019743006.1 amyloid fiber anchoring/assembly protein TapA -
  AB4922_RS11180 (AB4922_11180) - 2186879..2187205 (+) 327 WP_039166025.1 DUF3889 domain-containing protein -
  AB4922_RS11185 (AB4922_11185) - 2187240..2187434 (-) 195 WP_008342191.1 YqzE family protein -
  AB4922_RS11190 (AB4922_11190) comGG 2187495..2187878 (-) 384 WP_113747189.1 competence type IV pilus minor pilin ComGG -
  AB4922_RS11195 (AB4922_11195) comGF 2187875..2188372 (-) 498 WP_113747188.1 competence type IV pilus minor pilin ComGF -
  AB4922_RS11200 (AB4922_11200) comGE 2188314..2188628 (-) 315 WP_368774525.1 competence type IV pilus minor pilin ComGE -
  AB4922_RS11205 (AB4922_11205) comGD 2188612..2189058 (-) 447 WP_035702770.1 competence type IV pilus minor pilin ComGD -
  AB4922_RS11210 (AB4922_11210) comGC 2189051..2189344 (-) 294 WP_008342186.1 competence type IV pilus major pilin ComGC Machinery gene
  AB4922_RS11215 (AB4922_11215) comGB 2189362..2190402 (-) 1041 WP_035390815.1 competence type IV pilus assembly protein ComGB -
  AB4922_RS11220 (AB4922_11220) comGA 2190383..2191453 (-) 1071 WP_368774526.1 competence type IV pilus ATPase ComGA Machinery gene
  AB4922_RS11225 (AB4922_11225) - 2191911..2192780 (-) 870 WP_007501231.1 STAS domain-containing protein -
  AB4922_RS11235 (AB4922_11235) - 2193006..2193386 (-) 381 WP_007501232.1 Spx/MgsR family RNA polymerase-binding regulatory protein -
  AB4922_RS11240 (AB4922_11240) - 2193599..2193841 (+) 243 WP_003217440.1 DUF2626 domain-containing protein -
  AB4922_RS11245 (AB4922_11245) - 2193890..2194528 (-) 639 WP_017357989.1 MBL fold metallo-hydrolase -
  AB4922_RS11250 (AB4922_11250) - 2194689..2194862 (+) 174 WP_003217333.1 DUF2759 domain-containing protein -
  AB4922_RS11255 (AB4922_11255) - 2194887..2195201 (-) 315 WP_017367597.1 MTH1187 family thiamine-binding protein -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 40338.71 Da        Isoelectric Point: 9.0418

>NTDB_id=1028035 AB4922_RS11220 WP_368774526.1 2190383..2191453(-) (comGA) [Bacillus aerius strain KW1]
MYGIEYLGQELLEEACRMRASDVHIVPKEKEASVSFRVDADLIQQRIIDKKSGERLIAHFKFLSSMDIGERRRPQNGSLA
VMLRRGQVFVRLSTLPTVNDESLVIRILPQDHVPKTKYLSLFPKASARLLSFLNHSHGLILFTGPTNSGKTTTLYSLIQF
AKKHFNRNIITLEDPVETRNEEVLQVQVNEKAGITYAAGLRAILRHDPDMIVLGEIRDAETARTAIRAALTGHLVMSTLH
AKNAKGALYRMLEFGVTMNELEQTMVAIAAQRLIELACPFCGETCELYCKLNRPVRRTNVFELLYGKELGECIKEAKGEY
AHSSYETLQRLIRKGVALGYLSKSTYHRWVYEEANL

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=1028035 AB4922_RS11220 WP_368774526.1 2190383..2191453(-) (comGA) [Bacillus aerius strain KW1]
TTGTATGGTATTGAATATTTGGGGCAAGAGCTGCTAGAAGAGGCGTGCCGCATGAGAGCATCTGATGTGCATATTGTTCC
GAAAGAAAAGGAAGCTTCAGTCTCTTTTCGTGTAGACGCTGACCTCATTCAGCAGCGGATCATTGACAAAAAGAGCGGAG
AGCGGCTCATTGCTCATTTCAAATTTTTATCTTCTATGGATATTGGTGAAAGAAGGAGACCACAAAATGGGTCATTGGCT
GTGATGCTAAGACGCGGTCAAGTGTTTGTTCGGCTTTCTACATTACCGACTGTAAATGATGAAAGTTTAGTGATTCGGAT
TTTACCGCAGGATCATGTGCCGAAAACAAAGTATTTGTCACTGTTCCCGAAGGCTTCAGCGAGATTATTATCGTTTCTGA
ATCATTCGCATGGGCTCATTTTATTTACTGGACCAACAAATTCAGGGAAAACGACAACACTTTATTCATTGATCCAGTTT
GCTAAAAAACATTTTAATCGAAATATTATTACCCTTGAAGATCCTGTGGAAACAAGAAATGAAGAAGTGTTGCAGGTTCA
AGTAAATGAAAAAGCTGGTATCACGTATGCGGCAGGTTTACGCGCTATTTTAAGACATGATCCAGATATGATTGTGCTTG
GAGAAATAAGAGATGCGGAAACAGCCAGAACAGCTATTAGAGCAGCTTTGACAGGCCATTTAGTCATGAGCACACTGCAT
GCAAAAAATGCAAAAGGAGCTCTTTATCGAATGCTGGAATTTGGTGTGACGATGAATGAACTCGAACAAACAATGGTTGC
CATTGCTGCTCAGCGGTTAATCGAACTCGCATGTCCATTTTGCGGCGAAACGTGTGAGCTTTATTGCAAACTAAATCGGC
CAGTCAGACGAACAAATGTATTTGAATTGCTTTACGGAAAGGAGCTTGGTGAGTGTATCAAAGAGGCAAAAGGAGAATAC
GCTCATTCGTCATACGAAACACTGCAAAGATTAATTCGGAAAGGAGTGGCACTCGGCTATTTATCAAAAAGCACATATCA
TCGCTGGGTTTATGAAGAAGCGAACCTCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(11-275)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Bacillus subtilis subsp. subtilis str. 168

64.607

100

0.646

Multiple sequence alignment