Detailed information NTG1027712

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3456_RS05045
• Genome accession: NZ_CP162632
• Coordinates: 1083165..1084208 (+)
• Length: 347 a.a.
• NCBI ID: WP_017723493.1
• Uniprot ID: A0A418IPK4
• Organism: Staphylococcus pseudoxylosus strain Hao 2022
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1078165..1089208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3456_RS05020 (AB3456_05020)	-	1079129..1079851 (+)	723	WP_017723488.1	type 1 glutamine amidotransferase	-
AB3456_RS05025 (AB3456_05025)	-	1080044..1081030 (-)	987	WP_017723489.1	aromatic acid exporter family protein	-
AB3456_RS05030 (AB3456_05030)	map	1081207..1081959 (+)	753	WP_017723490.1	type I methionyl aminopeptidase	-
AB3456_RS05035 (AB3456_05035)	-	1082064..1082450 (+)	387	WP_017723491.1	hypothetical protein	-
AB3456_RS05040 (AB3456_05040)	liaF	1082467..1083168 (+)	702	WP_368679796.1	cell wall-active antibiotics response protein LiaF	-
AB3456_RS05045 (AB3456_05045)	vraS	1083165..1084208 (+)	1044	WP_017723493.1	sensor histidine kinase	Regulator
AB3456_RS05050 (AB3456_05050)	vraR	1084198..1084827 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
AB3456_RS05055 (AB3456_05055)	-	1085097..1086242 (-)	1146	WP_017723495.1	YihY/virulence factor BrkB family protein	-
AB3456_RS05060 (AB3456_05060)	-	1086598..1086882 (-)	285	WP_017723496.1	hypothetical protein	-
AB3456_RS05065 (AB3456_05065)	-	1086889..1087353 (-)	465	WP_017723497.1	low molecular weight protein-tyrosine-phosphatase	-
AB3456_RS05070 (AB3456_05070)	-	1087488..1087691 (+)	204	WP_017723498.1	DUF1128 family protein	-
AB3456_RS05075 (AB3456_05075)	-	1087709..1088947 (+)	1239	WP_107551833.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40051.58 Da
• Isoelectric Point: 6.4215

>NTDB_id=1027712 AB3456_RS05045 WP_017723493.1 1083165..1084208(+) (vraS) [Staphylococcus pseudoxylosus strain Hao 2022]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1027712 AB3456_RS05045 WP_017723493.1 1083165..1084208(+) (vraS) [Staphylococcus pseudoxylosus strain Hao 2022]
ATGAATCACTATATTAGAGCAATAGGTTCAATGTTGATATTAGTTTATAGTACATTTTTTGCCATATTTTTTATTGATAA
AGTATTTGTTAACATCATGTACTTTCAAGGTATGTTTTATACGCAAATATTTGGTATACCCGTCTTATTATTTTTAAATC
TAATGGTTATTTTACTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAGCAAAACCATTGGTTAAAAGAC
CAAATAGAAAGGTCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACAAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGTTAGCACGCGAACTACATGATTCGGTGAGT
CAACAGTTGTTCGCAGCTAGCATGATGTTATCAGCGATAAAAGAAACAAAATTAGAAGCACCATTAGATCAACAAATTCC
AGTACTAGAAAAAATGATACAAGATTCTCAGCTAGAGATGAGAGCTTTATTATTACATTTAAGACCTTTAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGATTTGGTTGTAGATTTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATCGAAGATCATTTGTTTAGAATCACACAAGAAGCTATATCGAATACGTTAAGGCA
TTCGAAAGGAACTAAAGTGACTATAGAGTTATTCAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTAGATGATAAAGTAGAACAAAGTTATGGCTTGAAAAATATGCGTGAACGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCATTACCTGACGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A418IPK4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	89.049	100	0.89