Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AS97_RS15970 Genome accession   NZ_CP007153
Coordinates   3630562..3631239 (+) Length   225 a.a.
NCBI ID   WP_059146712.1    Uniprot ID   A0ABN1BWI9
Organism   Streptomyces sp. AgN23     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3625562..3636239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AS97_RS15950 (AS97_30860) - 3626133..3626798 (+) 666 WP_210565150.1 TetR family transcriptional regulator -
  AS97_RS15955 (AS97_30865) - 3626899..3628104 (+) 1206 WP_059146709.1 alpha/beta hydrolase -
  AS97_RS15960 (AS97_30870) - 3628190..3629188 (+) 999 WP_210565152.1 DUF4429 domain-containing protein -
  AS97_RS15965 (AS97_30875) - 3629189..3630565 (+) 1377 WP_059146711.1 sensor histidine kinase -
  AS97_RS15970 (AS97_48130) vraR 3630562..3631239 (+) 678 WP_059146712.1 response regulator transcription factor Regulator
  AS97_RS15975 (AS97_48135) - 3631365..3632576 (+) 1212 WP_210565154.1 alpha/beta hydrolase -
  AS97_RS15980 (AS97_30900) - 3632801..3633844 (-) 1044 WP_086706994.1 aldo/keto reductase -
  AS97_RS15985 (AS97_30905) - 3633841..3634302 (-) 462 WP_059146715.1 MerR family transcriptional regulator -
  AS97_RS15990 (AS97_30910) - 3634451..3635263 (+) 813 WP_059146716.1 serine hydrolase domain-containing protein -
  AS97_RS15995 (AS97_30915) - 3635453..3636121 (-) 669 WP_125759751.1 pirin family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24222.99 Da        Isoelectric Point: 6.5012

>NTDB_id=102608 AS97_RS15970 WP_059146712.1 3630562..3631239(+) (vraR) [Streptomyces sp. AgN23]
MTIKVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGREGVAVSRRTHPDVVLMDVRMPEMDGLEAARQLLDPPRGVIHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARQRPAPRRDGPAARRGG
LTPRETEVLELIARGLSNQEIAESLVLAEQTVKTHIGRVLAKLGLRDRAQAVIFAYESGLVTPGH

Nucleotide


Download         Length: 678 bp        

>NTDB_id=102608 AS97_RS15970 WP_059146712.1 3630562..3631239(+) (vraR) [Streptomyces sp. AgN23]
ATGACCATCAAGGTGATCATCGTCGACGACCAGGCGATGGTGCGGGCCGGGTTCGCCGCCCTGCTCGCCGCGCAGAGCGA
TATCGACGTCGTCGGCGAGGCGCCCGACGGGCGGGAGGGCGTGGCGGTCAGCCGGCGCACCCACCCCGATGTGGTGCTGA
TGGACGTCCGGATGCCCGAGATGGACGGGCTCGAGGCGGCCCGGCAGCTCCTGGACCCACCGCGCGGGGTCATCCACCGG
CCCAAGGTCCTGATGCTCACCACCTTCGACGTGGACGACTACGTCTACGAGGCGCTGCGCGCCGGGGCCAGCGGCTTTCT
GCTGAAGGACGCCCCACCGGCCGATCTGATCTCCGCGGTCCGGGTGGTCGCGGCGGGCGAGGCGCTGCTCGCCCCGTCCG
TCACCCGCCGGCTGATCGCCGACTTCGCCCGCCAGCGCCCCGCTCCGCGCCGCGACGGCCCGGCCGCGCGGCGCGGTGGG
CTGACGCCGCGTGAGACCGAGGTGCTGGAGCTGATCGCGCGGGGCCTGTCCAACCAGGAGATCGCCGAGTCGCTGGTGCT
CGCGGAGCAGACGGTGAAGACGCATATCGGCCGGGTGCTGGCCAAGCTGGGGCTGCGCGACCGCGCCCAAGCGGTGATCT
TCGCCTATGAATCGGGCCTGGTGACGCCGGGTCATTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.144

98.667

0.436
  degU Bacillus subtilis subsp. subtilis str. 168

39.207

100

0.396

Multiple sequence alignment