Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   AB3447_RS07235 Genome accession   NZ_CP162456
Coordinates   1436999..1437568 (-) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain TUM20915     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1431999..1442568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3447_RS07195 (AB3447_07195) - 1432473..1433081 (-) 609 WP_000020302.1 class I SAM-dependent methyltransferase -
  AB3447_RS07200 (AB3447_07200) rplL 1433256..1433624 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  AB3447_RS07205 (AB3447_07205) rplJ 1433667..1434167 (-) 501 WP_001273087.1 50S ribosomal protein L10 -
  AB3447_RS07210 (AB3447_07210) rplA 1434439..1435131 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  AB3447_RS07215 (AB3447_07215) rplK 1435339..1435761 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  AB3447_RS07220 (AB3447_07220) nusG 1435942..1436490 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  AB3447_RS07225 (AB3447_07225) secE 1436503..1436685 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  AB3447_RS07230 (AB3447_07230) rpmG 1436741..1436884 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  AB3447_RS07235 (AB3447_07235) sigH 1436999..1437568 (-) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  AB3447_RS07240 (AB3447_07240) - 1437649..1438173 (-) 525 WP_000664738.1 NYN domain-containing protein -
  AB3447_RS07245 (AB3447_07245) rlmB 1438173..1438919 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  AB3447_RS07250 (AB3447_07250) - 1438927..1439331 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  AB3447_RS07255 (AB3447_07255) cysS 1439324..1440724 (-) 1401 WP_000631973.1 cysteine--tRNA ligase -
  AB3447_RS07260 (AB3447_07260) cysE 1440708..1441355 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=1025955 AB3447_RS07235 WP_000872877.1 1436999..1437568(-) (sigH) [Staphylococcus aureus strain TUM20915]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1025955 AB3447_RS07235 WP_000872877.1 1436999..1437568(-) (sigH) [Staphylococcus aureus strain TUM20915]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment