Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   DQL18_RS04320 Genome accession   NZ_LS483486
Coordinates   814993..817824 (+) Length   943 a.a.
NCBI ID   WP_050838133.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12194     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 809993..822824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL18_RS04285 (NCTC12194_00864) bamC 810062..810709 (-) 648 WP_005668207.1 outer membrane protein assembly factor BamC -
  DQL18_RS04290 (NCTC12194_00865) dapA 810820..811716 (-) 897 WP_005653399.1 4-hydroxy-tetrahydrodipicolinate synthase -
  DQL18_RS04295 (NCTC12194_00866) bcp 811817..812284 (+) 468 WP_005668209.1 thioredoxin-dependent thiol peroxidase -
  DQL18_RS04300 (NCTC12194_00867) exbB 812453..812905 (+) 453 WP_005648856.1 TonB-system energizer ExbB -
  DQL18_RS04305 (NCTC12194_00868) exbD 812909..813352 (+) 444 WP_005648853.1 TonB system transport protein ExbD -
  DQL18_RS04310 (NCTC12194_00869) - 813362..814156 (+) 795 WP_005653402.1 energy transducer TonB -
  DQL18_RS04315 (NCTC12194_00870) ssb 814334..814840 (-) 507 WP_005668849.1 single-stranded DNA-binding protein Machinery gene
  DQL18_RS04320 (NCTC12194_00871) uvrA 814993..817824 (+) 2832 WP_050838133.1 excinuclease ABC subunit UvrA Machinery gene
  DQL18_RS04325 (NCTC12194_00872) hap 818143..822318 (+) 4176 WP_042594188.1 adhesion and penetration autotransporter Hap -

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104307.27 Da        Isoelectric Point: 7.2761

>NTDB_id=1025945 DQL18_RS04320 WP_050838133.1 814993..817824(+) (uvrA) [Haemophilus influenzae strain NCTC12194]
MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDSIEGLS
PAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRCPDHNVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKG
EHLKILENIAAQGYIRARIDGEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVADMDNP
KAEELIFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTISLAGGAVKGWDRRNFYYYQM
LTSLAKHYHFDVEAPYESLPKKIQHIIMQGSGKEEIEFQYMNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKN
ISNRPCIDCGGSRLRSEARNVYIGKTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLCNLGNTVIVVEHDEDAIRAADHIIDI
GPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEIPKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTG
VSGSGKSTLINDTLFPLAQNALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPE
ARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFF
DAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEQVAKVKSSHTARFLKPILEKP

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=1025945 DQL18_RS04320 WP_050838133.1 814993..817824(+) (uvrA) [Haemophilus influenzae strain NCTC12194]
ATGGAAAATATCGATATTCGCGGGGCTAGAACCCATAACCTGAAAAATATTAATTTAACTATTCCACGCAATAAACTTGT
GGTGATTACTGGGCTTTCAGGTTCGGGAAAATCCTCTTTAGCCTTTGATACACTTTATGCGGAAGGGCAACGCCGCTATG
TTGAATCTCTTTCGGCGTATGCGCGTCAATTTTTGTCTTTAATGGAAAAGCCTGATGTGGATTCTATTGAGGGACTTTCC
CCTGCAATTTCCATTGAACAAAAATCTACCTCACACAATCCACGTTCTACGGTGGGAACAATTACGGAAATTTACGATTA
TTTACGTTTATTGTTTGCACGAGTAGGGGAGCCACGTTGTCCCGATCATAATGTTCCATTAACGGCACAAACAATTAGTC
AAATGGTGGATAAAGTATTAAGTTTGCCAGAAGACAGTAAGATGATGTTACTTGCGCCAGTTGTCAAAAATCGAAAAGGC
GAACATCTCAAGATTTTAGAAAATATTGCTGCGCAAGGTTATATTCGTGCGCGTATTGATGGCGAAATTTGCGATTTATC
TGATCCGCCAAAATTAGCCTTACAGAAAAAACATACTATTGAAGTAGTGGTTGATCGTTTTAAAGTGCGGTCAGATTTAG
CAACACGTTTAGCAGAGTCTTTTGAAACCGCATTAGAGCTTTCTGGTGGCACTGCGATTGTGGCAGATATGGATAATCCG
AAAGCGGAAGAATTAATTTTTTCAGCAAATTTTGCCTGTCCGCATTGTGGTTATTCTGTGCCAGAATTAGAGCCTCGTTT
GTTTTCCTTTAACAATCCTGCAGGTGCTTGCCCAACTTGTGATGGCTTGGGTGTGCAGCAATATTTTGATGAAGATCGTG
TGGTACAAAATCCAACTATTTCTCTTGCTGGTGGTGCGGTAAAAGGTTGGGATCGTCGTAATTTCTATTATTATCAAATG
CTTACATCATTGGCGAAACATTATCATTTTGATGTTGAAGCCCCTTATGAATCTTTGCCAAAGAAAATTCAACATATCAT
TATGCAGGGTTCAGGCAAAGAGGAAATTGAATTCCAATATATGAATGATCGTGGCGATGTGGTTATTCGCAAGCACCCTT
TTGAAGGGATTTTGAATAATATGGCTCGCCGATATAAAGAAACGGAATCAATGTCGGTGCGTGAAGAATTAGCGAAAAAT
ATTAGCAATCGACCTTGTATAGATTGTGGCGGTTCTCGTTTGCGATCCGAAGCGCGTAATGTGTATATTGGAAAAACCAA
TTTGCCGATAATTGCGGAAAAAAGCATTGGCGAAACCCTCGAATTTTTTACCGCACTTTCTCTCACTGGTCAAAAAGCAC
AAATTGCGGAAAAAATTCTTAAAGAAATCCGCGAGCGTTTGCAGTTTTTAGTCAATGTTGGTTTGAATTATCTTTCTCTT
TCTCGTTCTGCTGAAACTCTTTCAGGTGGGGAGGCGCAACGTATTCGCCTTGCGAGTCAAATTGGTGCGGGACTTGTTGG
CGTAATGTATGTATTAGATGAACCCTCTATTGGCTTGCACCAACGTGATAATGAACGCTTACTTAATACGTTAATTCATT
TGTGTAATCTTGGTAATACGGTAATTGTCGTGGAACACGATGAAGACGCGATTCGTGCAGCTGACCATATTATTGATATT
GGGCCTGGTGCTGGCGTGCATGGCGGACAAGTTATTGCACAAGGAAATGCCGATGAAATTATGCTGAATCCAAATTCCAT
CACAGGAAAATTTTTATCGGGTGCAGATAAAATCGAAATCCCGAAAAAACGCACCGCACTTGATAAGAAAAAATGGCTCA
AACTTAAAGGTGCATCAGGTAATAACTTAAAAAATGTGAATTTAGATATTCCCGTTGGTTTGTTTACTTGCGTAACTGGT
GTGTCTGGTTCAGGAAAATCCACACTTATTAATGACACCTTATTTCCACTTGCGCAAAATGCGTTAAATAGAGCTGAAAA
AACCGATTACGCACCTTATCAATCTATTGAGGGATTAGAACATTTCGATAAAGTTATTGATATTAACCAAAGCCCAATTG
GACGTACGCCACGTTCAAATCCAGCCACTTATACAGGCTTATTTACCCCAATTCGCGAGCTTTTTGCAGGTGTGCCAGAG
GCACGTGCGCGCGGTTATAATCCTGGGCGTTTTAGCTTTAACGTACGGGGTGGACGCTGTGAAGCCTGTCAGGGCGATGG
TGTACTCAAAGTTGAAATGCACTTTTTGCCCGATGTTTATGTTCCTTGCGACCAATGTAAAGGTAAACGCTATAATCGCG
AAACCTTAGAAATTCGTTACAAAGGCAAAACCATCCATCAGGTGTTAGATATGACAGTGGAAGAAGCTCGCGAGTTTTTT
GATGCGATTCCAATGATTGCAAGAAAATTACAAACCTTGATGGATGTGGGATTATCCTATATTCGATTAGGTCAATCTTC
CACAACACTTTCAGGCGGCGAAGCACAACGCGTTAAGCTAGCGACCGAGCTTTCTAAACGTGATACGGGTAAAACTTTGT
ATATTCTAGATGAACCGACGACTGGTTTGCATTTCGCTGACATTAAGCAATTACTTGAAGTACTGCATCGATTACGCGAC
CAAGGAAATACTATAGTCGTCATTGAACACAATCTTGATGTGATTAAAACCGCAGACTGGATTGTCGATCTTGGCCCAGA
GGGAGGCAGTGGCGGCGGACAAATTATTGCGACGGGTACACCAGAACAAGTTGCTAAAGTAAAAAGTTCCCACACCGCTC
GCTTCCTTAAACCGATTTTAGAAAAACCTTAG

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(130-237)

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.915

99.682

0.567
  uvrA Streptococcus pneumoniae TIGR4

56.915

99.682

0.567
  uvrA Streptococcus pneumoniae D39

56.915

99.682

0.567

Multiple sequence alignment