Detailed information NTG1025581

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AB3446_RS00935
• Genome accession: NZ_CP162440
• Coordinates: 177525..178511 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain TUM22457
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 172525..183511

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3446_RS00910 (AB3446_00910)	opp4B	172739..173701 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
AB3446_RS00915 (AB3446_00915)	opp4C	173713..174594 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
AB3446_RS00920 (AB3446_00920)	trpS	174636..175625 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
AB3446_RS00925 (AB3446_00925)	spxA	175919..176314 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
AB3446_RS00930 (AB3446_00930)	mecA	176685..177404 (+)	720	WP_001217728.1	adaptor protein MecA	-
AB3446_RS00935 (AB3446_00935)	coiA	177525..178511 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
AB3446_RS00940 (AB3446_00940)	pepF	178559..180367 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
AB3446_RS00945 (AB3446_00945)	yjbH	180827..181633 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
AB3446_RS00950 (AB3446_00950)	-	181656..182021 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
AB3446_RS00955 (AB3446_00955)	-	182125..182718 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
AB3446_RS00960 (AB3446_00960)	-	182904..183251 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1025581 AB3446_RS00935 WP_000959282.1 177525..178511(+) (coiA) [Staphylococcus aureus strain TUM22457]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1025581 AB3446_RS00935 WP_000959282.1 177525..178511(+) (coiA) [Staphylococcus aureus strain TUM22457]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976