Detailed information NTG1025571

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AB3435_RS13200
• Genome accession: NZ_CP162438
• Coordinates: 2632603..2633589 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain TUM22458
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 2627603..2638589

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3435_RS13175 (AB3435_13175)	-	2627863..2628210 (-)	348	WP_001242103.1	hypothetical protein	-
AB3435_RS13180 (AB3435_13180)	-	2628396..2628989 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
AB3435_RS13185 (AB3435_13185)	-	2629093..2629458 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
AB3435_RS13190 (AB3435_13190)	yjbH	2629481..2630287 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
AB3435_RS13195 (AB3435_13195)	pepF	2630747..2632555 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
AB3435_RS13200 (AB3435_13200)	coiA	2632603..2633589 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
AB3435_RS13205 (AB3435_13205)	mecA	2633710..2634429 (-)	720	WP_001217728.1	adaptor protein MecA	-
AB3435_RS13210 (AB3435_13210)	spxA	2634800..2635195 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
AB3435_RS13215 (AB3435_13215)	trpS	2635489..2636478 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
AB3435_RS13220 (AB3435_13220)	opp4C	2636520..2637401 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
AB3435_RS13225 (AB3435_13225)	opp4B	2637413..2638375 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1025571 AB3435_RS13200 WP_000959282.1 2632603..2633589(-) (coiA) [Staphylococcus aureus strain TUM22458]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1025571 AB3435_RS13200 WP_000959282.1 2632603..2633589(-) (coiA) [Staphylococcus aureus strain TUM22458]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976