Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   AB3435_RS06025 Genome accession   NZ_CP162438
Coordinates   1225499..1226068 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain TUM22458     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1220499..1231068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3435_RS06000 (AB3435_06000) cysE 1221712..1222359 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  AB3435_RS06005 (AB3435_06005) cysS 1222343..1223743 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  AB3435_RS06010 (AB3435_06010) - 1223736..1224140 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  AB3435_RS06015 (AB3435_06015) rlmB 1224148..1224894 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  AB3435_RS06020 (AB3435_06020) - 1224894..1225418 (+) 525 WP_000664737.1 NYN domain-containing protein -
  AB3435_RS06025 (AB3435_06025) sigH 1225499..1226068 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  AB3435_RS06030 (AB3435_06030) rpmG 1226183..1226326 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  AB3435_RS06035 (AB3435_06035) secE 1226382..1226564 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  AB3435_RS06040 (AB3435_06040) nusG 1226577..1227125 (+) 549 WP_368409922.1 transcription termination/antitermination protein NusG -
  AB3435_RS06045 (AB3435_06045) rplK 1227306..1227728 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  AB3435_RS06050 (AB3435_06050) rplA 1227936..1228628 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  AB3435_RS06055 (AB3435_06055) rplJ 1228900..1229400 (+) 501 WP_368409923.1 50S ribosomal protein L10 -
  AB3435_RS06060 (AB3435_06060) rplL 1229443..1229811 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  AB3435_RS06065 (AB3435_06065) - 1229986..1230594 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1025543 AB3435_RS06025 WP_000872882.1 1225499..1226068(+) (sigH) [Staphylococcus aureus strain TUM22458]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1025543 AB3435_RS06025 WP_000872882.1 1225499..1226068(+) (sigH) [Staphylococcus aureus strain TUM22458]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment