Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DQL12_RS08395 Genome accession   NZ_LS483450
Coordinates   1565843..1566520 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1560843..1571520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS08355 - 1561002..1561631 (-) 630 WP_000762092.1 NAD(P)-dependent oxidoreductase -
  DQL12_RS12325 - 1561870..1562245 (+) 376 Protein_1574 hypothetical protein -
  DQL12_RS08375 - 1562502..1562643 (+) 142 Protein_1575 MazG-like protein -
  DQL12_RS08380 - 1562650..1562826 (+) 177 WP_050218600.1 MazG-like protein -
  DQL12_RS08385 thrS 1562884..1564827 (+) 1944 WP_000608355.1 threonine--tRNA ligase -
  DQL12_RS08390 - 1564876..1565850 (-) 975 WP_000887972.1 HAMP domain-containing histidine kinase -
  DQL12_RS08395 braR 1565843..1566520 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  DQL12_RS08400 - 1566676..1567749 (+) 1074 WP_050218598.1 DUF2974 domain-containing protein -
  DQL12_RS08405 - 1567840..1568142 (-) 303 WP_000281601.1 hypothetical protein -
  DQL12_RS08410 - 1568211..1568648 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  DQL12_RS08415 - 1568724..1569566 (-) 843 WP_000160932.1 metallophosphoesterase family protein -
  DQL12_RS08420 - 1569678..1570328 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  DQL12_RS08430 - 1570447..1571184 (+) 738 WP_000749123.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=1025328 DQL12_RS08395 WP_000548991.1 1565843..1566520(-) (braR) [Streptococcus pneumoniae strain 4041STDY6583227]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=1025328 DQL12_RS08395 WP_000548991.1 1565843..1566520(-) (braR) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369