Detailed information NTG1025206

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AB3445_RS04465
• Genome accession: NZ_CP162422
• Coordinates: 880174..881046 (-)
• Length: 290 a.a.
• NCBI ID: WP_000593192.1
• Uniprot ID: A0A140HKN1
• Organism: Staphylococcus aureus strain TUM22723
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	881118..882290	880174..881046	flank	72

Gene organization within MGE regions

Location: 880174..882290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3445_RS04465 (AB3445_04465)	dprA	880174..881046 (-)	873	WP_000593192.1	DNA-processing protein DprA	Machinery gene
AB3445_RS04470 (AB3445_04470)	-	881118..882290 (-)	1173	WP_000195429.1	IS256-like element IS256 family transposase	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 33564.99 Da
• Isoelectric Point: 9.5094

>NTDB_id=1025206 AB3445_RS04465 WP_000593192.1 880174..881046(-) (dprA) [Staphylococcus aureus strain TUM22723]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide

• Length: 873 bp

>NTDB_id=1025206 AB3445_RS04465 WP_000593192.1 880174..881046(-) (dprA) [Staphylococcus aureus strain TUM22723]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCTGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-279)

3D structure

• AlphaFold DB: A0A140HKN1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Staphylococcus aureus MW2	100	100	1
dprA	Staphylococcus aureus N315	99.655	100	0.997