Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   AB3454_RS07470 Genome accession   NZ_CP162418
Coordinates   1484445..1485014 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain TUM22750     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1479445..1490014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3454_RS07445 (AB3454_07445) cysE 1480658..1481305 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  AB3454_RS07450 (AB3454_07450) cysS 1481289..1482689 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  AB3454_RS07455 (AB3454_07455) - 1482682..1483086 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  AB3454_RS07460 (AB3454_07460) rlmB 1483094..1483840 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  AB3454_RS07465 (AB3454_07465) - 1483840..1484364 (+) 525 WP_000664738.1 NYN domain-containing protein -
  AB3454_RS07470 (AB3454_07470) sigH 1484445..1485014 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  AB3454_RS07475 (AB3454_07475) rpmG 1485129..1485272 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  AB3454_RS07480 (AB3454_07480) secE 1485328..1485510 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  AB3454_RS07485 (AB3454_07485) nusG 1485523..1486071 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  AB3454_RS07490 (AB3454_07490) rplK 1486252..1486674 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  AB3454_RS07495 (AB3454_07495) rplA 1486882..1487574 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  AB3454_RS07500 (AB3454_07500) rplJ 1487846..1488346 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  AB3454_RS07505 (AB3454_07505) rplL 1488389..1488757 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  AB3454_RS07510 (AB3454_07510) - 1488932..1489540 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=1025113 AB3454_RS07470 WP_000872877.1 1484445..1485014(+) (sigH) [Staphylococcus aureus strain TUM22750]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1025113 AB3454_RS07470 WP_000872877.1 1484445..1485014(+) (sigH) [Staphylococcus aureus strain TUM22750]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment