Detailed information NTG0102471

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: ECRM12581_RS25280
• Genome accession: NZ_CP007136
• Coordinates: 4924081..4925106 (-)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli O145:H28 str. RM12581
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4919081..4930106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECRM12581_RS25255 (ECRM12581_24865)	rraA	4919495..4919980 (-)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
ECRM12581_RS25260 (ECRM12581_24870)	menA	4920073..4920999 (-)	927	WP_001308187.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
ECRM12581_RS25265 (ECRM12581_24875)	hslU	4921066..4922397 (-)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
ECRM12581_RS25270 (ECRM12581_24880)	hslV	4922407..4922937 (-)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
ECRM12581_RS25275 (ECRM12581_24885)	ftsN	4923030..4923989 (-)	960	WP_000068838.1	cell division protein FtsN	-
ECRM12581_RS25280 (ECRM12581_24890)	cytR	4924081..4925106 (-)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
ECRM12581_RS25285 (ECRM12581_24900)	priA	4925262..4927460 (-)	2199	WP_001400571.1	primosomal protein N'	Machinery gene
ECRM12581_RS25290 (ECRM12581_24905)	rpmE	4927663..4927875 (+)	213	WP_000710769.1	50S ribosomal protein L31	-
ECRM12581_RS25295 (ECRM12581_24910)	yiiX	4927936..4928544 (-)	609	WP_000702305.1	YiiX family permuted papain-like enzyme	-
ECRM12581_RS25300 (ECRM12581_24915)	metJ	4928604..4928921 (-)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=102471 ECRM12581_RS25280 WP_000644904.1 4924081..4925106(-) (cytR) [Escherichia coli O145:H28 str. RM12581]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=102471 ECRM12581_RS25280 WP_000644904.1 4924081..4925106(-) (cytR) [Escherichia coli O145:H28 str. RM12581]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCTCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCAGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGCCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628