Detailed information NTG1024704

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: AB1F57_RS10620
• Genome accession: NZ_CP162268
• Coordinates: 2099256..2100548 (-)
• Length: 430 a.a.
• NCBI ID: WP_367985730.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZY1909104
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	2101308..2102653	2099256..2100548	flank	760

Gene organization within MGE regions

Location: 2099256..2102653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F57_RS10620 (AB1F57_10620)	comFA/cflA	2099256..2100548 (-)	1293	WP_367985730.1	DEAD/DEAH box helicase	Machinery gene
AB1F57_RS10625 (AB1F57_10625)	-	2100605..2101237 (+)	633	WP_367985731.1	YigZ family protein	-
AB1F57_RS10630 (AB1F57_10630)	-	2101308..2102653 (+)	1346	WP_367985732.1	IS3 family transposase	-

Sequence

Protein

• Length: 430 a.a.
• Molecular weight: 48921.30 Da
• Isoelectric Point: 7.6110

>NTDB_id=1024704 AB1F57_RS10620 WP_367985730.1 2099256..2100548(-) (comFA/cflA) [Streptococcus sp. ZY1909104]
MKELENYYGRLFTKYQLTAEERQAAQTLPSMTEGGACFRCSTAFSDRHCLPNGAYYCRECILLGRVRSDEELYYFPQQDF
PENACLKWSGQLTDWQQKISNGLCANIEKRRPTLVHAVTGAGKTEMIYHAVAQVIDHGGAVCLASPRIDVCIELYKRLQQ
DFAVPISLLHGQSDPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAVDNAVKADGLQVFLTATSTDEL
DRKVKSSQLERLSLPRRFHGNPLIVPEKVWFSQFDQSLKKDKLVVKLKQAIRNQRKTSFPLLIFLPEISKGQEFVAILER
EFPDEKIGFVSSQMENRLEIVQGFRDRTITILVSTTILERGVTFPMVDVMVVQANHYLYTSSSLVQIGGRVGRSMDRPTG
LLLFFHEGSTRAIEKAIAEIKFMNKEAGYV

Nucleotide

• Length: 1293 bp

>NTDB_id=1024704 AB1F57_RS10620 WP_367985730.1 2099256..2100548(-) (comFA/cflA) [Streptococcus sp. ZY1909104]
ATGAAAGAACTAGAAAATTATTATGGACGACTGTTTACCAAGTATCAATTGACGGCTGAAGAGCGCCAAGCAGCTCAGAC
CTTACCTAGCATGACAGAGGGGGGCGCTTGTTTTCGTTGTTCGACTGCATTTTCGGACCGCCATTGTTTGCCAAACGGGG
CCTACTATTGCCGGGAATGTATCCTGCTAGGCAGGGTGCGGTCAGATGAGGAACTCTATTATTTTCCCCAGCAGGATTTC
CCAGAAAATGCCTGTCTCAAGTGGTCTGGTCAGCTGACTGATTGGCAGCAGAAGATTTCAAACGGGCTCTGTGCCAATAT
TGAAAAACGGCGCCCGACCCTGGTTCATGCCGTGACGGGGGCTGGAAAGACGGAGATGATTTACCATGCAGTAGCGCAAG
TCATTGACCATGGCGGGGCAGTTTGTCTGGCCAGTCCCAGAATTGATGTCTGTATTGAGCTTTATAAGCGGCTACAACAA
GATTTCGCTGTTCCCATCAGCCTCCTTCATGGCCAGTCGGATCCTTATTTTCGGACGCCGCTTGTGGTCGCTACCACCCA
CCAGTTGCTCAAGTTTTACCAGGCCTTTGATTTGGTCTTAATCGATGAGGTGGATGCCTTTCCCTATGCGGACAATCCCA
TGCTCTACCGGGCAGTAGACAATGCCGTCAAAGCAGACGGGCTCCAGGTTTTCCTGACAGCGACCTCGACGGATGAGCTG
GATAGGAAGGTCAAATCCAGCCAATTGGAACGGCTCAGTTTGCCCAGACGCTTTCACGGCAATCCCTTGATTGTGCCAGA
AAAGGTCTGGTTCAGCCAATTTGACCAGAGCCTGAAAAAGGACAAGCTGGTTGTCAAGCTCAAGCAAGCTATCAGAAACC
AGCGAAAAACAAGTTTTCCCTTGCTGATTTTTCTGCCAGAAATTTCCAAAGGCCAGGAATTTGTAGCGATTTTGGAGCGA
GAATTTCCTGATGAGAAAATCGGTTTTGTATCCAGTCAGATGGAAAATCGACTGGAGATTGTTCAAGGTTTTCGCGACCG
CACCATTACTATCCTGGTTTCAACAACGATTCTGGAGCGAGGTGTGACCTTTCCCATGGTTGATGTCATGGTGGTCCAGG
CCAACCACTATCTCTATACATCGTCCAGTTTAGTGCAAATTGGAGGCCGAGTCGGGCGGTCCATGGATCGTCCAACAGGC
TTGCTCCTCTTTTTTCACGAGGGTTCGACCCGTGCCATTGAAAAAGCAATCGCTGAAATCAAATTTATGAACAAGGAGGC
CGGCTATGTCTAA

Domains

Predicted by InterproScan.

• Type III restriction enzyme, res subunit (ResIII) (91-235)

• Helicase conserved C-terminal domain (Helicase_C) (291-393)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis SK321	68.213	100	0.684
comFA/cflA	Streptococcus mitis NCTC 12261	67.981	100	0.681
comFA/cflA	Streptococcus pneumoniae D39	67.053	100	0.672
comFA/cflA	Streptococcus pneumoniae R6	67.053	100	0.672
comFA/cflA	Streptococcus pneumoniae TIGR4	67.053	100	0.672
comFA/cflA	Streptococcus pneumoniae Rx1	67.053	100	0.672
comFA	Lactococcus lactis subsp. cremoris KW2	52.03	91.628	0.477
comFA	Latilactobacillus sakei subsp. sakei 23K	38.837	100	0.388