Detailed information NTG1024485

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: DQN28_RS06890
• Genome accession: NZ_LS483430
• Coordinates: 1366569..1369397 (-)
• Length: 942 a.a.
• NCBI ID: WP_111686355.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12044
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1361569..1374397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN28_RS06860 (NCTC12044_01364)	-	1362246..1363211 (+)	966	WP_002988504.1	LacI family DNA-binding transcriptional regulator	-
DQN28_RS06865 (NCTC12044_01365)	nusB	1363352..1363804 (-)	453	WP_002983167.1	transcription antitermination factor NusB	-
DQN28_RS06870 (NCTC12044_01366)	-	1363797..1364186 (-)	390	WP_002983163.1	Asp23/Gls24 family envelope stress response protein	-
DQN28_RS06875 (NCTC12044_01367)	efp	1364232..1364789 (-)	558	WP_002988496.1	elongation factor P	-
DQN28_RS06880 (NCTC12044_01368)	-	1364885..1365346 (-)	462	WP_002988493.1	deoxycytidylate deaminase	-
DQN28_RS06885 (NCTC12044_01369)	-	1365380..1366453 (-)	1074	WP_111686354.1	M24 family metallopeptidase	-
DQN28_RS06890 (NCTC12044_01370)	uvrA	1366569..1369397 (-)	2829	WP_111686355.1	excinuclease ABC subunit UvrA	Machinery gene
DQN28_RS06895 (NCTC12044_01371)	prx	1369623..1369805 (-)	183	WP_011184907.1	hypothetical protein	Regulator
DQN28_RS06900 (NCTC12044_01372)	sda3	1370043..1370843 (+)	801	WP_011285611.1	streptodornase Sda3	-
DQN28_RS06905 (NCTC12044_01373)	-	1371115..1371549 (+)	435	WP_011017966.1	hypothetical protein	-
DQN28_RS06910 (NCTC12044_01374)	-	1371599..1372465 (-)	867	WP_011888701.1	DUF334 domain-containing protein	-
DQN28_RS06915 (NCTC12044_01375)	-	1372453..1372977 (-)	525	WP_011017840.1	Panacea domain-containing protein	-
DQN28_RS06920 (NCTC12044_01376)	-	1373117..1374319 (-)	1203	WP_011054730.1	glucosaminidase domain-containing protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 103962.16 Da
• Isoelectric Point: 6.1359

>NTDB_id=1024485 DQN28_RS06890 WP_111686355.1 1366569..1369397(-) (uvrA) [Streptococcus pyogenes strain NCTC12044]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKGKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=1024485 DQN28_RS06890 WP_111686355.1 1366569..1369397(-) (uvrA) [Streptococcus pyogenes strain NCTC12044]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTCGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAACAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGATGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAAAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGGGATTTAGTTCT
TTATGGTTCAGGGGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGTGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCGACACAGATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGCCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGTCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTACAAAGGAAAAAATATCGCAGAAGTCCTTGATATGACTGTGGATGATGCCTTGGTATTTTTC
TCTGCTATTCCTAAAATCGCTCGAAAAATTCAAACGATTAAGGATGTTGGACTTGGTTATGTGACCTTAGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTGGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGCAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCTACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.713	100	0.847
uvrA	Streptococcus pneumoniae TIGR4	84.713	100	0.847
uvrA	Streptococcus pneumoniae D39	84.713	100	0.847