Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQN36_RS03360 Genome accession   NZ_LS483425
Coordinates   650067..650729 (+) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain NCTC13737     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 645067..655729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN36_RS03340 (NCTC13737_00657) - 645941..647941 (+) 2001 WP_111704094.1 potassium transporter Kup -
  DQN36_RS03345 (NCTC13737_00658) - 647965..648243 (-) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  DQN36_RS03350 (NCTC13737_00659) - 648233..649009 (-) 777 WP_010922438.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQN36_RS03355 (NCTC13737_00660) - 649127..649867 (+) 741 WP_002989170.1 lysophospholipid acyltransferase family protein -
  DQN36_RS03360 (NCTC13737_00661) comEA/celA/cilE 650067..650729 (+) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  DQN36_RS03365 (NCTC13737_00662) comEC/celB 650710..652953 (+) 2244 WP_111704095.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQN36_RS03370 (NCTC13737_00663) holA 653024..654064 (+) 1041 WP_111694871.1 DNA polymerase III subunit delta -
  DQN36_RS03375 (NCTC13737_00664) sodA 654161..654766 (+) 606 WP_002983977.1 superoxide dismutase SodA -
  DQN36_RS03380 (NCTC13737_00665) - 654933..655088 (+) 156 WP_231872675.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=1024306 DQN36_RS03360 WP_002995626.1 650067..650729(+) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC13737]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1024306 DQN36_RS03360 WP_002995626.1 650067..650729(+) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC13737]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405