Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQN75_RS02000 Genome accession   NZ_LS483420
Coordinates   381990..382772 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain NCTC13739     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 376990..387772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN75_RS01980 (NCTC13739_00393) - 377325..378290 (-) 966 WP_023078713.1 asparaginase -
  DQN75_RS01985 (NCTC13739_00394) - 378362..379750 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  DQN75_RS01990 (NCTC13739_00395) - 379875..380327 (-) 453 WP_002992571.1 universal stress protein -
  DQN75_RS01995 (NCTC13739_00396) - 380558..381772 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  DQN75_RS02000 (NCTC13739_00397) codY 381990..382772 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQN75_RS02005 (NCTC13739_00398) - 382919..383473 (+) 555 WP_002992568.1 cysteine hydrolase family protein -
  DQN75_RS02015 (NCTC13739_00399) - 383932..384252 (+) 321 Protein_337 putative PEP-binding protein -
  DQN75_RS02020 (NCTC13739_00400) gatC 384484..384786 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQN75_RS02025 (NCTC13739_00401) gatA 384786..386252 (+) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQN75_RS02030 (NCTC13739_00402) gatB 386252..387691 (+) 1440 WP_003052542.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=1024107 DQN75_RS02000 WP_002983278.1 381990..382772(+) (codY) [Streptococcus pyogenes strain NCTC13739]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1024107 DQN75_RS02000 WP_002983278.1 381990..382772(+) (codY) [Streptococcus pyogenes strain NCTC13739]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment