Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DQN54_RS07940 Genome accession   NZ_LS483417
Coordinates   1497776..1498453 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain NCTC11902     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1492776..1503453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN54_RS07905 (NCTC11902_01519) - 1492938..1493567 (-) 630 WP_000762094.1 NAD(P)-dependent oxidoreductase -
  DQN54_RS07910 (NCTC11902_01520) - 1493805..1494005 (+) 201 WP_001826938.1 hypothetical protein -
  DQN54_RS07925 (NCTC11902_01522) - 1494436..1494759 (+) 324 WP_000422781.1 hypothetical protein -
  DQN54_RS07930 (NCTC11902_01523) thrS 1494817..1496760 (+) 1944 WP_000608358.1 threonine--tRNA ligase -
  DQN54_RS07935 (NCTC11902_01524) - 1496809..1497783 (-) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  DQN54_RS07940 (NCTC11902_01525) braR 1497776..1498453 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  DQN54_RS07945 (NCTC11902_01526) - 1498609..1499682 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  DQN54_RS07950 (NCTC11902_01527) - 1499773..1500075 (-) 303 WP_000281608.1 hypothetical protein -
  DQN54_RS07955 (NCTC11902_01528) - 1500144..1500581 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  DQN54_RS07960 (NCTC11902_01529) - 1500657..1501499 (-) 843 WP_000160944.1 metallophosphoesterase family protein -
  DQN54_RS07965 (NCTC11902_01530) - 1501611..1502261 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  DQN54_RS12150 - 1502242..1502433 (+) 192 WP_001820758.1 hypothetical protein -
  DQN54_RS07975 (NCTC11902_01531) - 1502459..1503106 (+) 648 WP_000260178.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=1023929 DQN54_RS07940 WP_000548959.1 1497776..1498453(-) (braR) [Streptococcus pneumoniae strain NCTC11902]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=1023929 DQN54_RS07940 WP_000548959.1 1497776..1498453(-) (braR) [Streptococcus pneumoniae strain NCTC11902]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment