Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DQM69_RS10085 Genome accession   NZ_LS483381
Coordinates   2075457..2077403 (-) Length   648 a.a.
NCBI ID   WP_109982790.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2070457..2082403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS10060 (NCTC10921_02010) - 2071215..2073128 (+) 1914 WP_019775059.1 ATP-binding cassette domain-containing protein -
  DQM69_RS10065 - 2073167..2073430 (+) 264 WP_109982789.1 hypothetical protein -
  DQM69_RS10070 (NCTC10921_02011) - 2073480..2073881 (+) 402 WP_019777428.1 helix-turn-helix domain-containing protein -
  DQM69_RS10075 (NCTC10921_02012) - 2073915..2074466 (-) 552 WP_002960562.1 DNA-3-methyladenine glycosylase I -
  DQM69_RS10080 (NCTC10921_02013) ruvA 2074635..2075225 (-) 591 WP_019769153.1 Holliday junction branch migration protein RuvA Machinery gene
  DQM69_RS10085 (NCTC10921_02014) hexB 2075457..2077403 (-) 1947 WP_109982790.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQM69_RS10090 (NCTC10921_02015) hexA 2077644..2080205 (-) 2562 WP_109982791.1 DNA mismatch repair protein MutS Machinery gene
  DQM69_RS10095 (NCTC10921_02016) - 2080192..2080545 (-) 354 WP_019787291.1 YlbF family regulator -
  DQM69_RS10100 (NCTC10921_02017) argR 2080538..2080972 (-) 435 WP_019775054.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73102.32 Da        Isoelectric Point: 5.5931

>NTDB_id=1021652 DQM69_RS10085 WP_109982790.1 2075457..2077403(-) (hexB) [Streptococcus sobrinus strain NCTC10921]
MSKIIELPEVLANQIAAGEVVERPSSVVKELVENAIDAGSTQITVEIEESGLKKIQVTDNGQGIENDDVALSLRRHATSK
IKNQADLFRIRTLGFRGEALPSIASISDLTIKTAVKGADHGTLLVAKGGEILSQEPISTPVGTKITVEDLFFNTPARLKY
MKSLQAELGHIVDVINRQSLGHPEIAFTLINDGRELTKTTGTGDLRQAIAGIYGLNTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIDIQIDPYLADVNVHPTKQEVRISKEKELMQLIRK
AIAESLREQDLIPDALENLAKSSVRKADKPVQTSLPLKQTNLYYDQARQDFFLKSDNQVAENQSNQPSRPVNQVDKAVKP
TDSVRQAQRPEPDVQDQEHPDIDFSKKTQTHKLMVRLDQEASSSFPELDYFGQMQGTYLFAQGQGGLYIIDQHAAQERVK
YEYYREKIGEVDSSLQQLLVPYLFEFRAEDFINLQEKMTLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESGVYEMCDM
LLLTDEVSIKVYRAELAIMMSCKRSIKANHALDDYSASNLLVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=1021652 DQM69_RS10085 WP_109982790.1 2075457..2077403(-) (hexB) [Streptococcus sobrinus strain NCTC10921]
ATGTCAAAAATTATTGAATTGCCAGAGGTTCTGGCCAATCAGATTGCTGCCGGTGAGGTTGTTGAGCGGCCCAGCAGCGT
TGTTAAAGAATTAGTCGAGAATGCTATCGATGCCGGTAGCACACAAATTACAGTTGAAATCGAAGAATCCGGTCTCAAGA
AAATTCAGGTGACCGACAACGGCCAAGGCATTGAAAATGACGATGTGGCCCTCAGTCTGCGTCGTCACGCCACCAGTAAA
ATCAAAAATCAGGCGGATCTCTTTCGGATTCGGACCTTGGGATTTCGGGGTGAGGCCCTGCCGTCAATTGCCTCAATTAG
CGATTTGACGATTAAGACAGCGGTCAAGGGTGCAGACCACGGGACCCTGCTGGTCGCTAAAGGCGGAGAAATCCTCTCCC
AAGAGCCTATCAGTACCCCTGTCGGCACTAAGATTACGGTTGAGGATCTCTTCTTTAATACTCCAGCCCGCCTCAAGTAC
ATGAAGTCCCTCCAGGCAGAGTTGGGGCACATTGTTGATGTCATCAATCGTCAAAGCCTGGGGCACCCCGAGATTGCCTT
TACCCTGATTAATGATGGGCGTGAGTTGACCAAGACCACCGGCACTGGTGACCTGCGTCAGGCCATTGCTGGTATCTATG
GTCTCAATACAGCTAAGAAGATGGTCGAAATTTCCAATAGTGACTTGGATTTCGAGGTATCAGGCTATGTCAGTCTGCCT
GAATTGACTAGAGCCAATCGCAACTACATCACCATCCTCATCAACGGTCGCTACATCAAGAATTTCCTTCTCAATCGGGC
CATTTTAGATGGCTATGGCTCCAAGCTCATGGTCGGTCGCTTTCCCCTAGCTGTGATTGACATCCAGATTGACCCCTATT
TGGCCGATGTCAATGTCCATCCAACCAAGCAGGAAGTCCGGATTTCTAAGGAAAAAGAGCTCATGCAGCTGATTCGCAAG
GCAATTGCTGAGAGCTTGCGAGAGCAGGATTTGATTCCAGATGCCTTGGAAAATCTGGCCAAATCTAGTGTTCGCAAGGC
TGACAAACCTGTTCAGACCAGCCTGCCGCTCAAGCAGACCAATCTCTATTACGACCAGGCCCGTCAGGATTTCTTCCTTA
AATCGGACAATCAAGTGGCAGAAAACCAGTCAAACCAGCCTTCTCGACCTGTCAATCAAGTTGACAAGGCTGTCAAGCCG
ACGGATTCTGTCAGACAAGCCCAAAGGCCTGAACCAGATGTCCAGGACCAGGAACATCCTGATATTGACTTTTCCAAGAA
GACTCAGACCCATAAATTGATGGTTCGCCTGGACCAAGAAGCAAGCTCAAGCTTCCCTGAGTTGGATTATTTTGGTCAGA
TGCAGGGCACCTATCTCTTTGCCCAAGGACAAGGTGGCCTTTATATCATTGACCAACACGCTGCTCAGGAGCGGGTCAAA
TACGAATACTACCGAGAAAAAATTGGTGAGGTTGACAGTTCTTTACAGCAGCTCTTGGTTCCCTATCTCTTTGAATTTCG
GGCGGAAGACTTCATTAACCTTCAAGAAAAAATGACTCTCCTCAACCAAGTGGGTATCTATCTAGAACCCTATGGTAACA
ATACCTTTATCCTGCGGGAGCACCCCATCTGGATGAAGGAGGAAGAGATTGAATCGGGTGTTTACGAGATGTGCGACATG
CTCCTTTTGACGGATGAGGTTTCTATCAAGGTCTATCGGGCTGAGCTAGCTATCATGATGAGCTGTAAACGCTCCATCAA
GGCCAACCATGCCCTAGATGACTATTCGGCCAGCAATCTTCTAGTCCAACTATCCCAATGTAAAAATCCCTATAATTGTC
CCCATGGCCGGCCGGTCCTGGTTAATTTCACCAAGTCTGATATGGAAAAAATGTTCCGTCGGATTCAAGAGAACCATACC
AGCCTAAGGGAACTGGGGAAATATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

71.516

100

0.721