Detailed information
Bioinformatically predicted
Overview
| Name | comB | Type | Regulator |
| Locus tag | ABVF41_RS08810 | Genome accession | NZ_CP160385 |
| Coordinates | 1786713..1787726 (+) | Length | 337 a.a. |
| NCBI ID | WP_002263739.1 | Uniprot ID | Q8DSA7 |
| Organism | Streptococcus mutans strain UA159-WCSS | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1741478..1820870 | 1786713..1787726 | within | 0 |
Gene organization within MGE regions
Location: 1741478..1820870
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABVF41_RS08590 (ABVF41_08590) | - | 1741609..1743048 (+) | 1440 | WP_002262658.1 | sucrose-6-phosphate hydrolase | - |
| ABVF41_RS08595 (ABVF41_08595) | - | 1743051..1744013 (+) | 963 | WP_002262659.1 | LacI family DNA-binding transcriptional regulator | - |
| ABVF41_RS08600 (ABVF41_08600) | nusB | 1744207..1744635 (-) | 429 | WP_002262660.1 | transcription antitermination factor NusB | - |
| ABVF41_RS08605 (ABVF41_08605) | - | 1744628..1745017 (-) | 390 | WP_002262661.1 | Asp23/Gls24 family envelope stress response protein | - |
| ABVF41_RS08610 (ABVF41_08610) | efp | 1745060..1745620 (-) | 561 | WP_002262662.1 | elongation factor P | - |
| ABVF41_RS08615 (ABVF41_08615) | - | 1745760..1746464 (+) | 705 | WP_002262663.1 | ion transporter | - |
| ABVF41_RS08620 (ABVF41_08620) | - | 1746512..1746964 (-) | 453 | WP_002262664.1 | deaminase | - |
| ABVF41_RS08625 (ABVF41_08625) | - | 1747134..1748198 (-) | 1065 | WP_002262665.1 | Xaa-Pro peptidase family protein | - |
| ABVF41_RS08630 (ABVF41_08630) | uvrA | 1748188..1751019 (-) | 2832 | WP_002262666.1 | excinuclease ABC subunit UvrA | - |
| ABVF41_RS08635 (ABVF41_08635) | - | 1751069..1751290 (+) | 222 | WP_019313410.1 | hypothetical protein | - |
| ABVF41_RS08640 (ABVF41_08640) | - | 1751690..1752634 (+) | 945 | WP_002262667.1 | magnesium transporter CorA family protein | - |
| ABVF41_RS08645 (ABVF41_08645) | - | 1752916..1753578 (+) | 663 | WP_002262668.1 | DUF1129 domain-containing protein | - |
| ABVF41_RS08650 (ABVF41_08650) | hdrR | 1753717..1754073 (+) | 357 | WP_002262669.1 | LytTR family transcriptional regulator HdrR | Regulator |
| ABVF41_RS08655 (ABVF41_08655) | hdrM | 1754070..1754756 (+) | 687 | WP_002262670.1 | hdrR negative regulator HdrM | Regulator |
| ABVF41_RS08660 (ABVF41_08660) | - | 1754764..1755483 (-) | 720 | WP_002262671.1 | TraX family protein | - |
| ABVF41_RS08665 (ABVF41_08665) | rpsR | 1755802..1756041 (-) | 240 | WP_000068664.1 | 30S ribosomal protein S18 | - |
| ABVF41_RS08670 (ABVF41_08670) | ssbA | 1756070..1756564 (-) | 495 | WP_002261867.1 | single-stranded DNA-binding protein | Machinery gene |
| ABVF41_RS08675 (ABVF41_08675) | rpsF | 1756582..1756872 (-) | 291 | WP_002261866.1 | 30S ribosomal protein S6 | - |
| ABVF41_RS08680 (ABVF41_08680) | - | 1757028..1757273 (-) | 246 | WP_002263367.1 | hypothetical protein | - |
| ABVF41_RS08685 (ABVF41_08685) | - | 1757578..1757781 (+) | 204 | WP_002263366.1 | hypothetical protein | - |
| ABVF41_RS08690 (ABVF41_08690) | mutY | 1758818..1759963 (+) | 1146 | WP_002263365.1 | A/G-specific adenine glycosylase | - |
| ABVF41_RS08695 (ABVF41_08695) | - | 1760151..1761200 (-) | 1050 | WP_002263364.1 | zinc-dependent alcohol dehydrogenase family protein | - |
| ABVF41_RS08700 (ABVF41_08700) | trxA | 1761298..1761612 (-) | 315 | WP_002263363.1 | thioredoxin | - |
| ABVF41_RS08705 (ABVF41_08705) | - | 1761687..1764017 (-) | 2331 | WP_002263362.1 | endonuclease MutS2 | - |
| ABVF41_RS08710 (ABVF41_08710) | - | 1764086..1764631 (-) | 546 | WP_002263361.1 | CvpA family protein | - |
| ABVF41_RS08715 (ABVF41_08715) | - | 1764628..1764933 (-) | 306 | WP_002263360.1 | hypothetical protein | - |
| ABVF41_RS08720 (ABVF41_08720) | rnhC | 1765129..1766040 (+) | 912 | WP_002271343.1 | ribonuclease HIII | - |
| ABVF41_RS08725 (ABVF41_08725) | lepB | 1766060..1766647 (+) | 588 | WP_002263358.1 | signal peptidase I | - |
| ABVF41_RS08730 (ABVF41_08730) | - | 1766733..1769096 (+) | 2364 | WP_002263357.1 | ATP-dependent RecD-like DNA helicase | - |
| ABVF41_RS08735 (ABVF41_08735) | - | 1769195..1769665 (+) | 471 | WP_002263356.1 | hypothetical protein | - |
| ABVF41_RS08740 (ABVF41_08740) | - | 1770542..1771534 (+) | 993 | WP_002263355.1 | PTS sugar transporter subunit IIB | - |
| ABVF41_RS08745 (ABVF41_08745) | - | 1771569..1772387 (+) | 819 | WP_002263354.1 | PTS mannose/fructose/sorbose transporter subunit IIC | - |
| ABVF41_RS08750 (ABVF41_08750) | - | 1772402..1773328 (+) | 927 | WP_002263353.1 | PTS system mannose/fructose/sorbose family transporter subunit IID | - |
| ABVF41_RS08755 (ABVF41_08755) | comA/nlmT | 1773660..1775951 (-) | 2292 | WP_002263352.1 | peptide cleavage/export ABC transporter | Regulator |
| ABVF41_RS08760 (ABVF41_08760) | - | 1776501..1776854 (-) | 354 | WP_002263351.1 | hypothetical protein | - |
| ABVF41_RS08765 (ABVF41_08765) | - | 1777173..1777541 (+) | 369 | WP_002263350.1 | DUF956 family protein | - |
| ABVF41_RS08770 (ABVF41_08770) | - | 1777778..1778851 (-) | 1074 | WP_002263349.1 | acyltransferase | - |
| ABVF41_RS08775 (ABVF41_08775) | serS | 1779375..1780655 (+) | 1281 | WP_002263348.1 | serine--tRNA ligase | - |
| ABVF41_RS08780 (ABVF41_08780) | - | 1781338..1781601 (-) | 264 | WP_002352361.1 | Blp family class II bacteriocin | - |
| ABVF41_RS08785 (ABVF41_08785) | - | 1781905..1782090 (-) | 186 | WP_002263346.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | - |
| ABVF41_RS08795 (ABVF41_08795) | - | 1783667..1783828 (-) | 162 | WP_002263734.1 | Blp family class II bacteriocin | - |
| ABVF41_RS08800 (ABVF41_08800) | - | 1783873..1784127 (-) | 255 | WP_002263733.1 | Blp family class II bacteriocin | - |
| ABVF41_RS08805 (ABVF41_08805) | - | 1784515..1786700 (+) | 2186 | Protein_1687 | peptide cleavage/export ABC transporter | - |
| ABVF41_RS08810 (ABVF41_08810) | comB | 1786713..1787726 (+) | 1014 | WP_002263739.1 | HlyD family efflux transporter periplasmic adaptor subunit | Regulator |
| ABVF41_RS08815 (ABVF41_08815) | - | 1787988..1788131 (-) | 144 | WP_002263740.1 | hypothetical protein | - |
| ABVF41_RS08820 (ABVF41_08820) | - | 1788198..1788350 (-) | 153 | WP_002263741.1 | hypothetical protein | - |
| ABVF41_RS08825 (ABVF41_08825) | - | 1788423..1789445 (-) | 1023 | WP_002263742.1 | thioredoxin family protein | - |
| ABVF41_RS08830 (ABVF41_08830) | - | 1789931..1790119 (-) | 189 | WP_002263743.1 | Blp family class II bacteriocin | - |
| ABVF41_RS08835 (ABVF41_08835) | - | 1790283..1790495 (-) | 213 | WP_002263744.1 | Blp family class II bacteriocin | - |
| ABVF41_RS08840 (ABVF41_08840) | - | 1790900..1791064 (-) | 165 | WP_002265308.1 | hypothetical protein | - |
| ABVF41_RS08845 (ABVF41_08845) | - | 1791504..1791716 (+) | 213 | Protein_1695 | IS3 family transposase | - |
| ABVF41_RS08850 (ABVF41_08850) | - | 1791839..1792243 (-) | 405 | WP_002263912.1 | hypothetical protein | - |
| ABVF41_RS08855 (ABVF41_08855) | - | 1792390..1792809 (-) | 420 | WP_002263913.1 | hypothetical protein | - |
| ABVF41_RS08860 (ABVF41_08860) | - | 1794190..1794591 (-) | 402 | WP_002310604.1 | hypothetical protein | - |
| ABVF41_RS08865 (ABVF41_08865) | cipB | 1794722..1794952 (-) | 231 | WP_002265368.1 | Blp family class II bacteriocin | Regulator |
| ABVF41_RS08870 (ABVF41_08870) | comC/blpC | 1795219..1795359 (+) | 141 | WP_002267610.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | Regulator |
| ABVF41_RS08875 (ABVF41_08875) | comD/blpH | 1795501..1796826 (-) | 1326 | WP_002262113.1 | GHKL domain-containing protein | Regulator |
| ABVF41_RS08880 (ABVF41_08880) | comE/blpR | 1796823..1797575 (-) | 753 | WP_002262114.1 | response regulator transcription factor | Regulator |
| ABVF41_RS08885 (ABVF41_08885) | - | 1798047..1798685 (-) | 639 | WP_002262115.1 | VTT domain-containing protein | - |
| ABVF41_RS08890 (ABVF41_08890) | - | 1798732..1799358 (-) | 627 | WP_002262116.1 | hypothetical protein | - |
| ABVF41_RS08895 (ABVF41_08895) | der | 1799433..1800743 (-) | 1311 | WP_002262117.1 | ribosome biogenesis GTPase Der | - |
| ABVF41_RS08900 (ABVF41_08900) | dnaI | 1800756..1801655 (-) | 900 | WP_002262118.1 | primosomal protein DnaI | - |
| ABVF41_RS08905 (ABVF41_08905) | - | 1801656..1802825 (-) | 1170 | WP_002262119.1 | DnaD domain protein | - |
| ABVF41_RS08910 (ABVF41_08910) | nrdR | 1802812..1803303 (-) | 492 | WP_002262120.1 | transcriptional regulator NrdR | - |
| ABVF41_RS08915 (ABVF41_08915) | covR | 1803673..1804365 (-) | 693 | WP_002262121.1 | response regulator GcrR | Regulator |
| ABVF41_RS08920 (ABVF41_08920) | - | 1804722..1805258 (-) | 537 | WP_002262122.1 | YceD family protein | - |
| ABVF41_RS08925 (ABVF41_08925) | - | 1805251..1805826 (-) | 576 | WP_002262123.1 | TetR/AcrR family transcriptional regulator | - |
| ABVF41_RS08930 (ABVF41_08930) | - | 1805934..1806641 (+) | 708 | WP_002262124.1 | ABC transporter ATP-binding protein | - |
| ABVF41_RS08935 (ABVF41_08935) | - | 1806643..1809255 (+) | 2613 | WP_002263841.1 | ABC transporter permease | - |
| ABVF41_RS08940 (ABVF41_08940) | htpX | 1809392..1810291 (-) | 900 | WP_002262126.1 | zinc metalloprotease HtpX | - |
| ABVF41_RS08945 (ABVF41_08945) | - | 1810301..1810861 (-) | 561 | WP_002262127.1 | LemA family protein | - |
| ABVF41_RS08950 (ABVF41_08950) | rsmG | 1810949..1811662 (+) | 714 | WP_002262128.1 | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG | - |
| ABVF41_RS08955 (ABVF41_08955) | - | 1811886..1812719 (-) | 834 | WP_002262129.1 | energy-coupling factor transporter transmembrane protein EcfT | - |
| ABVF41_RS08960 (ABVF41_08960) | - | 1812712..1814388 (-) | 1677 | WP_002262130.1 | ABC transporter ATP-binding protein | - |
| ABVF41_RS08965 (ABVF41_08965) | - | 1814417..1814962 (-) | 546 | WP_002262131.1 | ECF-type riboflavin transporter substrate-binding protein | - |
| ABVF41_RS08970 (ABVF41_08970) | - | 1814972..1815817 (-) | 846 | WP_002262132.1 | S-adenosyl-l-methionine hydroxide adenosyltransferase family protein | - |
| ABVF41_RS08975 (ABVF41_08975) | - | 1815941..1816717 (-) | 777 | WP_002262133.1 | carbon-nitrogen family hydrolase | - |
| ABVF41_RS08980 (ABVF41_08980) | - | 1816785..1817474 (-) | 690 | WP_002262134.1 | methionine ABC transporter permease | - |
| ABVF41_RS08985 (ABVF41_08985) | - | 1817476..1818540 (-) | 1065 | WP_002262135.1 | methionine ABC transporter ATP-binding protein | - |
| ABVF41_RS08990 (ABVF41_08990) | - | 1818533..1819906 (-) | 1374 | WP_002262136.1 | M20/M25/M40 family metallo-hydrolase | - |
Sequence
Protein
Download Length: 337 a.a. Molecular weight: 38498.13 Da Isoelectric Point: 10.7202
>NTDB_id=1020622 ABVF41_RS08810 WP_002263739.1 1786713..1787726(+) (comB) [Streptococcus mutans strain UA159-WCSS]
MNPNLFKSAEFYRRRYHNFATVLIIPLVCLLVFLFIFLLFAKKEVTVLSDGEISPIKVIDVIQSKSDYPISENNLTDNHA
VKKRDVLIQYVNPAANTRQGGNNQNQNQSQNKQNKNQQQNNKNQKNGNQGQKNQNQNQNKKDQKNNNQSQQNKQGQKKTN
QSQNQQNKNQNKNQSQNKQNGNQNQNNWNQNNQNDKVTASQDGVIHTNPKYEGENLIPRGTEIAQLYPDINKTRQVLITY
YVSSKDVTRLKQGQKTHLALTKVGNDQISIRGKINSIASAATTTKKGNVFKVTAKAKVSKKDSQTIKYGLQGKTITVVEK
KTFFDYYKDKLLNKNQK
MNPNLFKSAEFYRRRYHNFATVLIIPLVCLLVFLFIFLLFAKKEVTVLSDGEISPIKVIDVIQSKSDYPISENNLTDNHA
VKKRDVLIQYVNPAANTRQGGNNQNQNQSQNKQNKNQQQNNKNQKNGNQGQKNQNQNQNKKDQKNNNQSQQNKQGQKKTN
QSQNQQNKNQNKNQSQNKQNGNQNQNNWNQNNQNDKVTASQDGVIHTNPKYEGENLIPRGTEIAQLYPDINKTRQVLITY
YVSSKDVTRLKQGQKTHLALTKVGNDQISIRGKINSIASAATTTKKGNVFKVTAKAKVSKKDSQTIKYGLQGKTITVVEK
KTFFDYYKDKLLNKNQK
Nucleotide
Download Length: 1014 bp
>NTDB_id=1020622 ABVF41_RS08810 WP_002263739.1 1786713..1787726(+) (comB) [Streptococcus mutans strain UA159-WCSS]
ATGAACCCAAATTTATTTAAAAGCGCTGAATTCTACCGAAGACGCTATCATAATTTTGCTACAGTTCTTATTATTCCTTT
GGTTTGTTTACTTGTATTTTTATTTATCTTTCTATTATTTGCTAAAAAAGAGGTCACTGTCTTGTCTGATGGCGAGATCT
CTCCCATTAAAGTAATTGATGTTATTCAATCTAAAAGTGATTATCCCATTTCTGAAAATAATTTAACAGATAATCACGCC
GTTAAAAAAAGGGATGTTCTCATCCAATATGTTAATCCAGCAGCAAATACAAGACAGGGCGGAAATAATCAGAATCAAAA
TCAATCTCAAAACAAGCAAAATAAGAATCAGCAGCAAAACAATAAGAATCAAAAAAACGGCAATCAAGGTCAAAAAAATC
AAAATCAGAACCAAAATAAAAAGGATCAGAAAAACAATAACCAATCTCAGCAAAACAAGCAAGGACAAAAGAAAACTAAT
CAATCCCAAAATCAGCAGAATAAGAATCAAAATAAAAACCAATCTCAAAACAAACAAAATGGGAATCAAAACCAAAATAA
CTGGAATCAGAATAATCAAAATGATAAAGTCACAGCCAGCCAAGATGGTGTTATCCATACCAACCCCAAATATGAAGGTG
AAAACTTAATTCCTCGGGGGACTGAAATCGCACAGCTCTATCCAGATATTAACAAAACAAGACAAGTTCTGATCACTTAT
TACGTCTCCTCTAAAGATGTCACCCGCCTCAAACAAGGCCAAAAGACTCATCTTGCTTTAACCAAGGTAGGAAATGATCA
AATTTCCATTAGAGGAAAAATTAATAGTATCGCTTCAGCTGCTACAACGACGAAAAAAGGCAATGTTTTTAAAGTGACAG
CTAAAGCAAAAGTTTCTAAAAAAGACAGCCAAACCATTAAATACGGCCTCCAGGGTAAAACCATCACAGTTGTTGAAAAA
AAGACTTTCTTTGATTATTATAAAGATAAACTGTTAAATAAAAATCAAAAATAA
ATGAACCCAAATTTATTTAAAAGCGCTGAATTCTACCGAAGACGCTATCATAATTTTGCTACAGTTCTTATTATTCCTTT
GGTTTGTTTACTTGTATTTTTATTTATCTTTCTATTATTTGCTAAAAAAGAGGTCACTGTCTTGTCTGATGGCGAGATCT
CTCCCATTAAAGTAATTGATGTTATTCAATCTAAAAGTGATTATCCCATTTCTGAAAATAATTTAACAGATAATCACGCC
GTTAAAAAAAGGGATGTTCTCATCCAATATGTTAATCCAGCAGCAAATACAAGACAGGGCGGAAATAATCAGAATCAAAA
TCAATCTCAAAACAAGCAAAATAAGAATCAGCAGCAAAACAATAAGAATCAAAAAAACGGCAATCAAGGTCAAAAAAATC
AAAATCAGAACCAAAATAAAAAGGATCAGAAAAACAATAACCAATCTCAGCAAAACAAGCAAGGACAAAAGAAAACTAAT
CAATCCCAAAATCAGCAGAATAAGAATCAAAATAAAAACCAATCTCAAAACAAACAAAATGGGAATCAAAACCAAAATAA
CTGGAATCAGAATAATCAAAATGATAAAGTCACAGCCAGCCAAGATGGTGTTATCCATACCAACCCCAAATATGAAGGTG
AAAACTTAATTCCTCGGGGGACTGAAATCGCACAGCTCTATCCAGATATTAACAAAACAAGACAAGTTCTGATCACTTAT
TACGTCTCCTCTAAAGATGTCACCCGCCTCAAACAAGGCCAAAAGACTCATCTTGCTTTAACCAAGGTAGGAAATGATCA
AATTTCCATTAGAGGAAAAATTAATAGTATCGCTTCAGCTGCTACAACGACGAAAAAAGGCAATGTTTTTAAAGTGACAG
CTAAAGCAAAAGTTTCTAAAAAAGACAGCCAAACCATTAAATACGGCCTCCAGGGTAAAACCATCACAGTTGTTGAAAAA
AAGACTTTCTTTGATTATTATAAAGATAAACTGTTAAATAAAAATCAAAAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB | Streptococcus mutans UA159 |
100 |
100 |
1 |
| comB/nlmE | Streptococcus mutans UA159 |
50.299 |
99.11 |
0.499 |