Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DQM48_RS02550 Genome accession   NZ_LS483348
Coordinates   465052..465702 (-) Length   216 a.a.
NCBI ID   WP_020916359.1    Uniprot ID   A0AB33AKJ9
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 460052..470702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS02525 (NCTC8738_00514) trpC 460280..461020 (+) 741 WP_058833333.1 indole-3-glycerol phosphate synthase TrpC -
  DQM48_RS02530 (NCTC8738_00515) - 461007..461588 (+) 582 WP_058833199.1 phosphoribosylanthranilate isomerase -
  DQM48_RS02535 (NCTC8738_00516) trpB 461662..462795 (+) 1134 Protein_424 tryptophan synthase subunit beta -
  DQM48_RS02540 (NCTC8738_00517) trpA 462799..463582 (+) 784 Protein_425 tryptophan synthase subunit alpha -
  DQM48_RS02545 (NCTC8738_00519) - 463618..464964 (-) 1347 WP_020916358.1 Nramp family divalent metal transporter -
  DQM48_RS02550 (NCTC8738_00520) cclA/cilC 465052..465702 (-) 651 WP_020916359.1 prepilin peptidase Machinery gene
  DQM48_RS02555 (NCTC8738_00521) - 465841..466365 (+) 525 WP_020916360.1 Dps family protein -
  DQM48_RS02560 (NCTC8738_00522) - 466496..466705 (+) 210 WP_006531568.1 YqgQ family protein -
  DQM48_RS02565 (NCTC8738_00523) - 466698..467666 (+) 969 WP_111698303.1 ROK family glucokinase -
  DQM48_RS02570 (NCTC8738_00524) - 467677..468057 (+) 381 WP_020916363.1 rhodanese-like domain-containing protein -
  DQM48_RS10290 (NCTC8738_00525) - 468072..468248 (+) 177 WP_231853159.1 hypothetical protein -
  DQM48_RS02575 (NCTC8738_00526) - 468303..469118 (+) 816 WP_228380506.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 24600.50 Da        Isoelectric Point: 5.5569

>NTDB_id=1019268 DQM48_RS02550 WP_020916359.1 465052..465702(-) (cclA/cilC) [Streptococcus lutetiensis strain NCTC8738]
MDTFLFFFLGASLASFIGLVVDRFLEESILFPASHCNTCGKQLRPLDMIPVLSQIFNHSRCHFCKSKIPLWYGIFEFVCG
LATALYYHDIIAPSSLFIFFFSMTLSLYDLKNQSFPLLIWLLPSASLLLFLPLNTVSIILLLLGIIAELFDIKIGSGDFF
YLASLSLFLDLESILWIVELGSLVGILYCLFDKNKRIPFIPFLFLGYLLVIIFKCD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1019268 DQM48_RS02550 WP_020916359.1 465052..465702(-) (cclA/cilC) [Streptococcus lutetiensis strain NCTC8738]
ATGGACACTTTTTTATTCTTTTTTCTTGGAGCATCGCTTGCTTCATTTATCGGATTAGTTGTTGATCGTTTTCTAGAGGA
ATCTATTTTATTTCCTGCTAGTCATTGTAATACCTGTGGTAAACAACTGAGACCGCTAGACATGATTCCAGTTCTTTCTC
AGATTTTTAATCATTCTCGCTGCCATTTTTGCAAAAGTAAAATTCCTTTATGGTATGGCATTTTTGAATTTGTCTGTGGG
CTCGCAACTGCTCTTTATTACCACGATATCATAGCACCATCTAGTCTCTTTATTTTCTTCTTTAGCATGACACTTAGTTT
ATATGATTTAAAAAACCAGTCCTTTCCTCTATTAATCTGGTTACTACCCAGTGCTTCTTTACTCCTTTTTCTTCCTCTTA
ATACGGTAAGTATTATTCTTCTTTTACTTGGGATCATAGCTGAGCTTTTTGACATAAAAATCGGTAGCGGTGATTTTTTC
TACCTAGCCAGTTTGAGTCTTTTTCTTGATTTGGAGAGCATTTTATGGATTGTTGAACTGGGTTCTTTGGTAGGAATTCT
GTATTGCCTTTTTGATAAAAACAAACGCATTCCCTTTATTCCTTTTCTATTTTTAGGCTATCTTTTAGTTATAATTTTTA
AGTGTGATTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33AKJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

43.256

99.537

0.431
  cclA/cilC Streptococcus pneumoniae Rx1

42.791

99.537

0.426
  cclA/cilC Streptococcus pneumoniae D39

42.791

99.537

0.426
  cclA/cilC Streptococcus pneumoniae R6

42.791

99.537

0.426
  cclA/cilC Streptococcus mitis SK321

42.857

97.222

0.417
  cclA/cilC Streptococcus mitis NCTC 12261

41.86

99.537

0.417

Multiple sequence alignment