Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DQL23_RS02840 Genome accession   NZ_LS483341
Coordinates   607634..608266 (+) Length   210 a.a.
NCBI ID   WP_060552932.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 602634..613266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS02820 (NCTC7865_00562) - 603176..603916 (+) 741 WP_060553304.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL23_RS02825 (NCTC7865_00563) stkP 603913..605760 (+) 1848 WP_060552934.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL23_RS02830 (NCTC7865_00564) liaF 605936..606634 (+) 699 WP_060553303.1 cell wall-active antibiotics response protein LiaF -
  DQL23_RS02835 (NCTC7865_00565) - 606631..607632 (+) 1002 WP_060552933.1 sensor histidine kinase -
  DQL23_RS02840 (NCTC7865_00566) vraR 607634..608266 (+) 633 WP_060552932.1 response regulator transcription factor Regulator
  DQL23_RS02845 (NCTC7865_00567) - 608354..609757 (+) 1404 WP_060552931.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQL23_RS02850 (NCTC7865_00568) - 609754..610140 (+) 387 WP_060552930.1 S1 RNA-binding domain-containing protein -
  DQL23_RS02855 (NCTC7865_00569) cysK 610177..611106 (-) 930 WP_008808600.1 cysteine synthase A -
  DQL23_RS02860 (NCTC7865_00570) - 611204..611836 (-) 633 WP_060552929.1 YigZ family protein -
  DQL23_RS02865 (NCTC7865_00571) comFA/cflA 611892..613193 (+) 1302 WP_060552928.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23777.36 Da        Isoelectric Point: 4.8067

>NTDB_id=1018739 DQL23_RS02840 WP_060552932.1 607634..608266(+) (vraR) [Streptococcus gordonii strain NCTC7865]
MKILLVDDHEMVRLGLKSYLDLQADVEVVAESSNGREGVELALELRPDVIIMDIVMPEMNGIEATMAILETWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADEILHAIRKVARGEIAIETEVSKKVQYHRNHIELHDDLTARERDILGLLAKGY
ENQRIADELYISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1018739 DQL23_RS02840 WP_060552932.1 607634..608266(+) (vraR) [Streptococcus gordonii strain NCTC7865]
ATGAAAATTTTATTAGTAGATGATCACGAAATGGTTCGTTTGGGATTAAAAAGCTACCTAGACTTACAAGCAGATGTTGA
AGTGGTGGCAGAAAGTTCTAATGGCCGTGAGGGAGTTGAGCTGGCTTTGGAGCTAAGACCAGATGTCATCATCATGGATA
TTGTTATGCCAGAGATGAATGGTATCGAGGCTACTATGGCTATTCTAGAAACTTGGCCAGAGGCAAAGATTTTGATTTTG
ACTTCCTACTTGGATAATGAAAAGATTTATCCTGTTCTGGATGCTGGAGCTAAAGGTTACATGCTGAAGACATCTAGTGC
AGATGAGATCTTACATGCTATCCGAAAAGTAGCTAGAGGAGAAATTGCGATTGAAACAGAAGTCAGCAAAAAAGTTCAGT
ACCATCGCAATCACATTGAATTACATGATGATTTAACCGCCCGAGAACGAGATATTTTGGGGCTTCTAGCCAAGGGCTAT
GAAAATCAACGCATTGCTGATGAACTTTATATTTCTCTAAAAACAGTAAAAACTCATGTTTCTAATATCTTATCAAAATT
GGAAGTGAGCGACCGGACTCAAGCGGTTGTCTATGCCTTCCAGCATCACTTAGTTCCTCAGGAAGACTTTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

39.732

100

0.424