Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DQL04_RS02705 Genome accession   NZ_LS483340
Coordinates   515326..515967 (+) Length   213 a.a.
NCBI ID   WP_047235722.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12062     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 510326..520967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL04_RS02685 (NCTC12062_00531) - 510873..511613 (+) 741 WP_002983660.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL04_RS02690 (NCTC12062_00532) pknB 511610..513517 (+) 1908 WP_047235721.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL04_RS02695 (NCTC12062_00533) liaF 513640..514332 (+) 693 WP_011054833.1 cell wall-active antibiotics response protein LiaF -
  DQL04_RS02700 (NCTC12062_00534) - 514329..515333 (+) 1005 WP_002991890.1 sensor histidine kinase -
  DQL04_RS02705 (NCTC12062_00535) vraR 515326..515967 (+) 642 WP_047235722.1 response regulator transcription factor Regulator
  DQL04_RS02710 (NCTC12062_00536) - 516004..517404 (+) 1401 WP_023079249.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQL04_RS02715 (NCTC12062_00537) - 517404..517781 (+) 378 WP_009880466.1 S1 RNA-binding domain-containing protein -
  DQL04_RS02720 (NCTC12062_00538) cysK 517799..518740 (-) 942 WP_111698560.1 cysteine synthase A -
  DQL04_RS02725 (NCTC12062_00539) - 518868..519500 (-) 633 WP_009880468.1 YigZ family protein -
  DQL04_RS02730 (NCTC12062_00540) comFA/cflA 519556..520881 (+) 1326 WP_047235723.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23785.45 Da        Isoelectric Point: 5.1641

>NTDB_id=1018667 DQL04_RS02705 WP_047235722.1 515326..515967(+) (vraR) [Streptococcus pyogenes strain NCTC12062]
MSKIKVILVDDHEMVRMGLKSFLNFQADIDVVGEASNGREGVDLALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1018667 DQL04_RS02705 WP_047235722.1 515326..515967(+) (vraR) [Streptococcus pyogenes strain NCTC12062]
ATGAGTAAGATAAAAGTGATATTGGTCGATGATCATGAAATGGTCCGCATGGGACTCAAGAGTTTTTTGAATTTTCAAGC
TGATATTGATGTCGTTGGTGAGGCCTCTAATGGACGTGAAGGGGTTGATTTAGCATTGGCTTTGAAGCCAGATGTTTTGG
TTATGGATCTAGTGATGCCAGAGTTAGGCGGTGTTGAGGCAACTTTAGAAGTCCTAAAAAAATGGAAAGAGGCTAAGGTA
CTTGTGTTAACTTCCTATCTAGATAATGAAAAGATATACCCTGTCATTGATGCAGGAGCGAAGGGTTATATGTTAAAAAC
ATCGAGTGCGGCTGAAATTTTAAATGCCATTCGCAAGGTTTCAAAGGGAGAGTTAGCCATTGAAACAGAAGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCATGAGGAACTAACAGCGCGTGAGTATGATATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACCCAAGCGGTTGTCTATGCTTTTCGACACCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.913

96.714

0.512
  degU Bacillus subtilis subsp. subtilis str. 168

36.726

100

0.39