Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DQL34_RS07910 Genome accession   NZ_LS483339
Coordinates   1491008..1491652 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1486008..1496652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS07885 (NCTC12958_01647) - 1488111..1489109 (-) 999 WP_111679664.1 NAD(P)/FAD-dependent oxidoreductase -
  DQL34_RS07890 (NCTC12958_01648) trmD 1489111..1489830 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DQL34_RS07895 (NCTC12958_01649) rimM 1489820..1490338 (-) 519 WP_084828975.1 ribosome maturation factor RimM -
  DQL34_RS07910 (NCTC12958_01652) vraR 1491008..1491652 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  DQL34_RS07915 (NCTC12958_01653) - 1491642..1492652 (-) 1011 WP_100262586.1 sensor histidine kinase -
  DQL34_RS07920 (NCTC12958_01654) liaF 1492649..1493347 (-) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  DQL34_RS12140 - 1493602..1493769 (-) 168 WP_014727613.1 potassium channel family protein -
  DQL34_RS07930 (NCTC12958_01655) stkP/pknB 1494405..1496276 (-) 1872 WP_084826071.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1018580 DQL34_RS07910 WP_002951384.1 1491008..1491652(-) (vraR) [Streptococcus thermophilus strain NCTC12958]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1018580 DQL34_RS07910 WP_002951384.1 1491008..1491652(-) (vraR) [Streptococcus thermophilus strain NCTC12958]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379