Detailed information NTG1016735

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQM44_RS06870
• Genome accession: NZ_LS483318
• Coordinates: 1337234..1339477 (-)
• Length: 747 a.a.
• NCBI ID: WP_044565459.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1332234..1344477

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM44_RS06850 (NCTC5370_01416)	-	1332843..1334063 (+)	1221	WP_015017200.1	DUF3114 domain-containing protein	-
DQM44_RS06855 (NCTC5370_01417)	-	1334184..1335245 (-)	1062	WP_046166020.1	serine hydrolase	-
DQM44_RS06860 (NCTC5370_01418)	sodA	1335412..1336017 (-)	606	WP_014612432.1	superoxide dismutase SodA	-
DQM44_RS06865 (NCTC5370_01419)	holA	1336107..1337153 (-)	1047	WP_046166021.1	DNA polymerase III subunit delta	-
DQM44_RS06870 (NCTC5370_01420)	comEC/celB	1337234..1339477 (-)	2244	WP_044565459.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQM44_RS06875 (NCTC5370_01421)	comEA	1339458..1340120 (-)	663	WP_003057999.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQM44_RS06880 (NCTC5370_01422)	-	1340517..1341257 (-)	741	WP_022554937.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
DQM44_RS06885 (NCTC5370_01423)	-	1341375..1342151 (+)	777	WP_080286812.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
DQM44_RS06890 (NCTC5370_01424)	-	1342141..1342419 (+)	279	WP_003061674.1	GIY-YIG nuclease family protein	-
DQM44_RS06895 (NCTC5370_01425)	-	1342443..1344443 (-)	2001	WP_022554940.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 84997.50 Da
• Isoelectric Point: 9.4078

>NTDB_id=1016735 DQM44_RS06870 WP_044565459.1 1337234..1339477(-) (comEC/celB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MNYRWTKWSPLPPIQLAFLVMALYYQIYCPSWLTCLLSSCLGMLLLKQFPQKTLCKVVMILALFAAVFVYRKHQLRQQLE
TQPLQVSQVALVPDSIRINGDQLAVIGRHGNHSYQLFYHFKHQTEARFFQKEYRWIVMHAKIVLDKAETSRNFRGFNYQS
FLAYQGIYRIGKVEQVEQLEVVSPKSVGDYLSSLRRQAIVHCQQSFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRGLTLLAIPLEWIKWIELPFACLYAALTGYSISVIRSLLQAQLGHLGIKGLDNLACAFLLVLL
WDAHALMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTLNASLVFGSPTSWHLLILVISFAILYDHRKIRQRVITCGLVIGLTLLS
VKYPLTNEVTFIDIGQGDSILVRDWTGKNLLIDVGGRLSFSSKEQWRQGHQTSNAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSQPSFVRRLRGLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGNGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIERYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLTRLEDR
EISYYRTDIQGAVRLTGWLNWHIETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=1016735 DQM44_RS06870 WP_044565459.1 1337234..1339477(-) (comEC/celB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGAACTATCGTTGGACTAAGTGGTCTCCCTTGCCTCCCATTCAACTAGCCTTTTTGGTAATGGCTCTTTATTATCAGAT
CTATTGTCCTAGCTGGTTGACTTGCTTACTTAGCAGTTGTTTAGGAATGTTACTATTGAAGCAGTTTCCTCAGAAGACCC
TCTGTAAGGTTGTTATGATTCTGGCCTTATTTGCTGCTGTCTTTGTTTATCGGAAACATCAGTTGAGACAGCAATTGGAA
ACACAACCTTTACAAGTGTCTCAGGTAGCATTGGTTCCGGATAGTATTCGAATTAATGGAGATCAATTAGCTGTTATTGG
GCGTCACGGTAATCATTCTTATCAGTTGTTTTATCATTTTAAACATCAAACGGAAGCCCGATTTTTCCAAAAAGAGTACC
GTTGGATAGTGATGCATGCCAAAATAGTATTGGACAAGGCTGAGACTTCCCGAAATTTTAGAGGATTTAATTACCAATCT
TTTTTAGCCTATCAGGGAATTTACAGGATAGGAAAAGTGGAACAAGTAGAGCAGCTTGAAGTGGTTTCACCAAAGTCAGT
AGGAGATTATTTATCTTCTTTGAGGCGACAGGCTATTGTCCATTGCCAACAATCCTTTCCAAAGCCCATGTCTCATTATT
TGACGGGACTCCTTTTCGGCTATTTGGATAAGTCCTTTGGTGAGATGACAGATTATTATAGTCAGCTTGGTATCATTCAT
CTTTTTGCCCTATCAGGGATGCAGGTTGGCTTCTTTTTAACCTGTTTTAGAAGAGGTTTGACGCTATTAGCTATTCCTCT
CGAATGGATTAAATGGATAGAGCTTCCCTTTGCCTGTCTATATGCTGCGCTGACAGGTTACAGTATTTCTGTTATTCGAA
GCCTTCTGCAGGCCCAATTAGGTCATCTAGGCATAAAAGGCTTAGATAATCTGGCTTGCGCTTTCTTACTTGTTCTTTTA
TGGGATGCTCATGCTTTGATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCCATGTCAATGGTCTTAACAGGGCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGTAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTTGGGAATACCCTCAATGCCTCCCTTGTTTTTGGAAGTCCGACCAGTTGGCACTTGCTTATCCTGGTGATTAGCT
TCGCTATTCTTTATGACCATCGGAAGATACGACAAAGAGTTATCACTTGCGGCTTGGTCATAGGCCTGACGCTTTTATCT
GTTAAATATCCTTTGACCAATGAAGTGACCTTTATCGATATTGGCCAGGGCGATAGTATTTTAGTGAGGGATTGGACAGG
AAAAAATCTCTTAATAGATGTAGGTGGGCGCCTTTCCTTTTCTTCAAAAGAGCAGTGGCGACAGGGGCACCAGACATCGA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACCATTGACCAATTACTAGTGACTCATGCGGAT
ACTGATCATATGGGGGATATAGAGGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGTAGTTTAAG
CCAGCCAAGCTTTGTTAGGCGGTTAAGGGGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAATTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGAACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGATTTGGAAAAAGAGGGAGAAAACGAGATCATAGAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCCTAACCCGTTTAGAGGATAGG
GAAATTTCTTATTATCGCACGGATATTCAAGGAGCTGTTCGGTTGACAGGATGGCTAAATTGGCATATTGAGACTGTTCG
TTGA

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

• Competence protein (Competence) (217-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	46.247	99.866	0.462
comEC/celB	Streptococcus mitis SK321	46.309	99.732	0.462
comEC/celB	Streptococcus pneumoniae TIGR4	45.722	100	0.458
comEC/celB	Streptococcus pneumoniae Rx1	45.455	100	0.455
comEC/celB	Streptococcus pneumoniae D39	45.455	100	0.455
comEC/celB	Streptococcus pneumoniae R6	45.455	100	0.455
comEC	Lactococcus lactis subsp. cremoris KW2	41.398	99.598	0.412