Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ABVR74_RS09375 Genome accession   NZ_CP159484
Coordinates   1914419..1916869 (-) Length   816 a.a.
NCBI ID   WP_098396276.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain CBA3648     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1909419..1921869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABVR74_RS09350 (ABVR74_09350) - 1910405..1910563 (-) 159 WP_179884634.1 hypothetical protein -
  ABVR74_RS09355 (ABVR74_09355) - 1910594..1910833 (-) 240 WP_098394067.1 hypothetical protein -
  ABVR74_RS09360 (ABVR74_09360) - 1911218..1912153 (-) 936 WP_165379818.1 tyrosine-type recombinase/integrase -
  ABVR74_RS09365 (ABVR74_09365) eno 1912241..1913542 (-) 1302 WP_010905473.1 surface-displayed alpha-enolase -
  ABVR74_RS09370 (ABVR74_09370) raiA 1913727..1914284 (-) 558 WP_003129564.1 ribosome-associated translation inhibitor RaiA -
  ABVR74_RS09375 (ABVR74_09375) clpC 1914419..1916869 (-) 2451 WP_098396276.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ABVR74_RS09380 (ABVR74_09380) - 1916859..1917314 (-) 456 WP_010905471.1 CtsR family transcriptional regulator -
  ABVR74_RS09385 (ABVR74_09385) greA 1917491..1917964 (-) 474 WP_033899645.1 transcription elongation factor GreA -
  ABVR74_RS09390 (ABVR74_09390) mltG 1918024..1919676 (-) 1653 WP_058220628.1 endolytic transglycosylase MltG -
  ABVR74_RS09395 (ABVR74_09395) rpoE 1919813..1920376 (-) 564 WP_012897344.1 DNA-directed RNA polymerase subunit delta -
  ABVR74_RS09400 (ABVR74_09400) - 1920593..1921105 (-) 513 WP_012897343.1 adenine phosphoribosyltransferase -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90420.79 Da        Isoelectric Point: 6.5300

>NTDB_id=1013835 ABVR74_RS09375 WP_098396276.1 1914419..1916869(-) (clpC) [Lactococcus lactis subsp. lactis strain CBA3648]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKVAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNNRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEALAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=1013835 ABVR74_RS09375 WP_098396276.1 1914419..1916869(-) (clpC) [Lactococcus lactis subsp. lactis strain CBA3648]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCCATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGGTGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAATCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGCTTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACATAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTTGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(357-453)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(19-69)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(96-144)

ATPase family associated with various cellular activities (AAA) (AAA)

(218-334)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-802)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

99.632

100

0.996
  clpC Streptococcus thermophilus LMD-9

50.421

100

0.513
  clpC Streptococcus thermophilus LMG 18311

50.301

100

0.512
  clpC Streptococcus pneumoniae Rx1

49.216

100

0.5
  clpC Streptococcus pneumoniae D39

49.216

100

0.5
  clpC Streptococcus pneumoniae TIGR4

49.095

100

0.499
  clpC Streptococcus mutans UA159

48.558

100

0.495
  clpC Bacillus subtilis subsp. subtilis str. 168

50.374

98.284

0.495
  clpE Streptococcus mutans UA159

47.692

79.657

0.38
  clpC Lactococcus lactis subsp. cremoris KW2

46.87

80.27

0.376
  clpE Streptococcus pneumoniae TIGR4

47.528

76.838

0.365
  clpE Streptococcus pneumoniae Rx1

47.528

76.838

0.365
  clpE Streptococcus pneumoniae D39

47.528

76.838

0.365
  clpE Streptococcus pneumoniae R6

47.528

76.838

0.365

Multiple sequence alignment