Detailed information NTG1013824

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: ABVR74_RS04185
• Genome accession: NZ_CP159484
• Coordinates: 802679..804154 (+)
• Length: 491 a.a.
• NCBI ID: WP_010906048.1
• Uniprot ID: A0A2A9ICZ0
• Organism: Lactococcus lactis subsp. lactis strain CBA3648
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 797679..809154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABVR74_RS04150 (ABVR74_04150)	-	797766..798602 (+)	837	WP_353891823.1	metallophosphoesterase	-
ABVR74_RS04155 (ABVR74_04155)	-	798715..799626 (+)	912	WP_058223280.1	CHAP domain-containing protein	-
ABVR74_RS04160 (ABVR74_04160)	-	799852..800214 (+)	363	WP_023188700.1	TIGR02328 family protein	-
ABVR74_RS04165 (ABVR74_04165)	-	800296..800760 (+)	465	WP_353891824.1	hypothetical protein	-
ABVR74_RS04170 (ABVR74_04170)	-	800916..801161 (+)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
ABVR74_RS04175 (ABVR74_04175)	-	801292..801822 (+)	531	WP_274998381.1	DUF177 domain-containing protein	-
ABVR74_RS04180 (ABVR74_04180)	covR	801978..802670 (+)	693	WP_003130756.1	response regulator transcription factor	Regulator
ABVR74_RS04185 (ABVR74_04185)	covS	802679..804154 (+)	1476	WP_010906048.1	HAMP domain-containing histidine kinase	Regulator
ABVR74_RS04190 (ABVR74_04190)	-	804337..805578 (+)	1242	WP_353891825.1	ammonium transporter	-
ABVR74_RS04195 (ABVR74_04195)	-	805710..806051 (+)	342	WP_010906046.1	P-II family nitrogen regulator	-
ABVR74_RS04200 (ABVR74_04200)	murD	806543..807895 (+)	1353	WP_003130748.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 491 a.a.
• Molecular weight: 56195.08 Da
• Isoelectric Point: 4.8253

>NTDB_id=1013824 ABVR74_RS04185 WP_010906048.1 802679..804154(+) (covS) [Lactococcus lactis subsp. lactis strain CBA3648]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide

• Length: 1476 bp

>NTDB_id=1013824 ABVR74_RS04185 WP_010906048.1 802679..804154(+) (covS) [Lactococcus lactis subsp. lactis strain CBA3648]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATAAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCGAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGTCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

• ArlS sensor domain (ArlS_N) (54-185)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (380-489)

• HAMP domain (HAMP) (208-258)

• His Kinase A (phospho-acceptor) domain (HisKA) (267-332)

3D structure

• AlphaFold DB: A0A2A9ICZ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	100	100	1