Detailed information NTG1013814

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: ABVR74_RS02795
• Genome accession: NZ_CP159484
• Coordinates: 535906..536607 (+)
• Length: 233 a.a.
• NCBI ID: WP_004255173.1
• Uniprot ID: S6FFV7
• Organism: Lactococcus lactis subsp. lactis strain CBA3648
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 530906..541607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABVR74_RS02780 (ABVR74_02780)	-	533301..534209 (+)	909	WP_058223188.1	diacylglycerol kinase family protein	-
ABVR74_RS02785 (ABVR74_02785)	-	534356..535042 (+)	687	WP_004255158.1	amino acid ABC transporter permease	-
ABVR74_RS02790 (ABVR74_02790)	-	535042..535776 (+)	735	WP_004255171.1	amino acid ABC transporter ATP-binding protein	-
ABVR74_RS02795 (ABVR74_02795)	mecA	535906..536607 (+)	702	WP_004255173.1	adaptor protein MecA	Regulator
ABVR74_RS02800 (ABVR74_02800)	-	536610..537941 (+)	1332	WP_021722251.1	MraY family glycosyltransferase	-
ABVR74_RS02805 (ABVR74_02805)	sufC	538116..538886 (+)	771	WP_004255181.1	Fe-S cluster assembly ATPase SufC	-
ABVR74_RS02810 (ABVR74_02810)	sufD	539024..540280 (+)	1257	WP_021722250.1	Fe-S cluster assembly protein SufD	-
ABVR74_RS02815 (ABVR74_02815)	-	540280..541497 (+)	1218	WP_058223190.1	cysteine desulfurase	-

Sequence

Protein

• Length: 233 a.a.
• Molecular weight: 27077.46 Da
• Isoelectric Point: 4.1246

>NTDB_id=1013814 ABVR74_RS02795 WP_004255173.1 535906..536607(+) (mecA) [Lactococcus lactis subsp. lactis strain CBA3648]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide

• Length: 702 bp

>NTDB_id=1013814 ABVR74_RS02795 WP_004255173.1 535906..536607(+) (mecA) [Lactococcus lactis subsp. lactis strain CBA3648]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-230)

3D structure

• AlphaFold DB: S6FFV7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Lactococcus lactis subsp. lactis strain DGCC12653	99.571	100	0.996
mecA	Lactococcus lactis subsp. cremoris KW2	96.996	100	0.97