Detailed information NTG1013537

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: U1770_RS13210
• Genome accession: NZ_CP159430
• Coordinates: 2644329..2645216 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN40
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2639329..2650216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U1770_RS13180 (U1770_13180)	-	2639348..2639440 (+)	93	WP_010956583.1	hypothetical protein	-
U1770_RS13185 (U1770_13185)	-	2639548..2640045 (-)	498	WP_001065268.1	glutathione peroxidase	-
U1770_RS13190 (U1770_13190)	-	2640055..2640315 (-)	261	WP_001791974.1	hypothetical protein	-
U1770_RS13195 (U1770_13195)	-	2640697..2640810 (-)	114	Protein_2559	hypothetical protein	-
U1770_RS13200 (U1770_13200)	-	2641469..2643469 (-)	2001	WP_000776751.1	ABC transporter permease	-
U1770_RS13205 (U1770_13205)	-	2643466..2644221 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
U1770_RS13210 (U1770_13210)	braS	2644329..2645216 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
U1770_RS13215 (U1770_13215)	braR	2645227..2645892 (-)	666	WP_196573306.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
U1770_RS13220 (U1770_13220)	-	2645918..2646118 (-)	201	WP_000604730.1	hypothetical protein	-
U1770_RS13225 (U1770_13225)	-	2646316..2647740 (+)	1425	WP_000953755.1	alkaline phosphatase	-
U1770_RS13230 (U1770_13230)	-	2647800..2647901 (-)	102	WP_000731976.1	SE2200 family small protein	-
U1770_RS13235 (U1770_13235)	-	2648023..2648478 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
U1770_RS13240 (U1770_13240)	-	2648723..2649484 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1013537 U1770_RS13210 WP_000143425.1 2644329..2645216(-) (braS) [Staphylococcus aureus strain BSN40]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1013537 U1770_RS13210 WP_000143425.1 2644329..2645216(-) (braS) [Staphylococcus aureus strain BSN40]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1