Detailed information NTG1013531

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: U1770_RS09310
• Genome accession: NZ_CP159430
• Coordinates: 1909582..1910625 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN40
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1904582..1915625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U1770_RS09280 (U1770_09280)	-	1905003..1906259 (-)	1257	WP_001795108.1	aminopeptidase	-
U1770_RS09285 (U1770_09285)	-	1906262..1906462 (-)	201	WP_000180460.1	DUF1128 family protein	-
U1770_RS09290 (U1770_09290)	-	1906609..1907073 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
U1770_RS09295 (U1770_09295)	-	1907080..1907355 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
U1770_RS09300 (U1770_09300)	-	1907633..1908850 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
U1770_RS09305 (U1770_09305)	vraR	1908963..1909592 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
U1770_RS09310 (U1770_09310)	vraS	1909582..1910625 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
U1770_RS09315 (U1770_09315)	liaF	1910622..1911323 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
U1770_RS09320 (U1770_09320)	-	1911338..1911724 (-)	387	WP_001110179.1	hypothetical protein	-
U1770_RS09325 (U1770_09325)	map	1911941..1912699 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
U1770_RS09330 (U1770_09330)	-	1913230..1914216 (+)	987	WP_322417460.1	aromatic acid exporter family protein	-
U1770_RS09335 (U1770_09335)	-	1914647..1915060 (-)	414	WP_001557448.1	hypothetical protein	-
U1770_RS09340 (U1770_09340)	-	1915089..1915199 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1013531 U1770_RS09310 WP_001017131.1 1909582..1910625(-) (vraS) [Staphylococcus aureus strain BSN40]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1013531 U1770_RS09310 WP_001017131.1 1909582..1910625(-) (vraS) [Staphylococcus aureus strain BSN40]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1