Detailed information NTG1013081

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: ABQ274_RS12530
• Genome accession: NZ_CP159281
• Coordinates: 2464191..2464892 (+)
• Length: 233 a.a.
• NCBI ID: WP_004255173.1
• Uniprot ID: S6FFV7
• Organism: Lactococcus lactis strain FNZ339
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2459191..2469892

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABQ274_RS12515 (ABQ274_12515)	-	2461586..2462494 (+)	909	WP_023164481.1	diacylglycerol kinase family protein	-
ABQ274_RS12520 (ABQ274_12520)	-	2462642..2463328 (+)	687	WP_004255158.1	amino acid ABC transporter permease	-
ABQ274_RS12525 (ABQ274_12525)	-	2463328..2464062 (+)	735	WP_004255171.1	amino acid ABC transporter ATP-binding protein	-
ABQ274_RS12530 (ABQ274_12530)	mecA	2464191..2464892 (+)	702	WP_004255173.1	adaptor protein MecA	Regulator
ABQ274_RS12535 (ABQ274_12535)	-	2464895..2466226 (+)	1332	WP_023164480.1	MraY family glycosyltransferase	-
ABQ274_RS12540 (ABQ274_12540)	sufC	2466401..2467171 (+)	771	WP_023164479.1	Fe-S cluster assembly ATPase SufC	-
ABQ274_RS12545 (ABQ274_12545)	sufD	2467309..2468565 (+)	1257	WP_353727270.1	Fe-S cluster assembly protein SufD	-
ABQ274_RS12550 (ABQ274_12550)	-	2468565..2469782 (+)	1218	WP_023164477.1	cysteine desulfurase	-

Sequence

Protein

• Length: 233 a.a.
• Molecular weight: 27077.46 Da
• Isoelectric Point: 4.1246

>NTDB_id=1013081 ABQ274_RS12530 WP_004255173.1 2464191..2464892(+) (mecA) [Lactococcus lactis strain FNZ339]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide

• Length: 702 bp

>NTDB_id=1013081 ABQ274_RS12530 WP_004255173.1 2464191..2464892(+) (mecA) [Lactococcus lactis strain FNZ339]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTCGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-230)

3D structure

• AlphaFold DB: S6FFV7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Lactococcus lactis subsp. lactis strain DGCC12653	99.571	100	0.996
mecA	Lactococcus lactis subsp. cremoris KW2	96.996	100	0.97