Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | V5233_RS00430 | Genome accession | NZ_CP158667 |
| Coordinates | 88838..90466 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain BSN25 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 39658..91837 | 88838..90466 | within | 0 |
Gene organization within MGE regions
Location: 39658..91837
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V5233_RS00180 (V5233_0000180) | ccrB | 39658..41286 (-) | 1629 | WP_001631035.1 | cassette chromosome recombinase CcrB | Machinery gene |
| V5233_RS00185 (V5233_0000185) | ccrA | 41283..42644 (-) | 1362 | WP_001631036.1 | cassette chromosome recombinase CcrA | Machinery gene |
| V5233_RS00190 (V5233_0000190) | - | 42831..43460 (-) | 630 | Protein_35 | hypothetical protein | - |
| V5233_RS00195 (V5233_0000195) | - | 43469..43807 (+) | 339 | Protein_36 | recombinase family protein | - |
| V5233_RS00200 (V5233_0000200) | - | 43919..44278 (-) | 360 | WP_196506795.1 | hypothetical protein | - |
| V5233_RS00205 (V5233_0000205) | - | 44485..44811 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| V5233_RS00210 (V5233_0000210) | - | 45141..47066 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| V5233_RS00215 (V5233_0000215) | - | 48161..48790 (+) | 630 | WP_001053439.1 | hypothetical protein | - |
| V5233_RS00220 (V5233_0000220) | - | 48805..49047 (+) | 243 | WP_000931963.1 | hypothetical protein | - |
| V5233_RS00225 (V5233_0000225) | - | 49446..50297 (+) | 852 | WP_000832687.1 | IS3 family transposase | - |
| V5233_RS00230 (V5233_0000230) | arcC | 50397..51326 (-) | 930 | WP_000036756.1 | carbamate kinase | - |
| V5233_RS00235 (V5233_0000235) | argF | 51346..52344 (-) | 999 | WP_000793596.1 | ornithine carbamoyltransferase | - |
| V5233_RS00240 (V5233_0000240) | - | 52382..53071 (-) | 690 | WP_000272781.1 | Crp/Fnr family transcriptional regulator | - |
| V5233_RS00245 (V5233_0000245) | arcD | 53113..54534 (-) | 1422 | WP_000344142.1 | arginine-ornithine antiporter | - |
| V5233_RS00250 (V5233_0000250) | arcA | 54620..55855 (-) | 1236 | WP_000249804.1 | arginine deiminase | - |
| V5233_RS00255 (V5233_0000255) | - | 56124..56570 (-) | 447 | WP_000711815.1 | arginine repressor | - |
| V5233_RS00260 (V5233_0000260) | - | 57143..57825 (+) | 683 | Protein_49 | type I restriction enzyme endonuclease domain-containing protein | - |
| V5233_RS00265 (V5233_0000265) | - | 58096..58527 (-) | 432 | WP_000475804.1 | universal stress protein | - |
| V5233_RS00270 (V5233_0000270) | - | 59409..59735 (-) | 327 | WP_000916431.1 | hypothetical protein | - |
| V5233_RS00275 (V5233_0000275) | - | 59751..60425 (+) | 675 | WP_001106065.1 | IS6 family transposase | - |
| V5233_RS00280 (V5233_0000280) | - | 60957..62213 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| V5233_RS00285 (V5233_0000285) | - | 62628..62867 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| V5233_RS00290 (V5233_0000290) | - | 62899..63573 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| V5233_RS00295 (V5233_0000295) | - | 63664..64647 (-) | 984 | Protein_56 | protein rep | - |
| V5233_RS00300 (V5233_0000300) | mobV | 64892..66154 (-) | 1263 | WP_316646156.1 | MobV family relaxase | - |
| V5233_RS00305 (V5233_0000305) | bleO | 66661..67065 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| V5233_RS00310 (V5233_0000310) | aadD1 | 67282..68052 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| V5233_RS00315 (V5233_0000315) | - | 68245..68919 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| V5233_RS00320 (V5233_0000320) | - | 69184..69927 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| V5233_RS00325 (V5233_0000325) | - | 70024..70452 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| V5233_RS00330 (V5233_0000330) | mecA | 70498..72507 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| V5233_RS00335 (V5233_0000335) | mecR1 | 72604..74361 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| V5233_RS00340 (V5233_0000340) | mecI | 74361..74732 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| V5233_RS00345 (V5233_0000345) | psm-mec | 74817..74885 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| V5233_RS00350 (V5233_0000350) | - | 75219..76349 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| V5233_RS00355 (V5233_0000355) | cstB | 76463..77797 (-) | 1335 | Protein_68 | persulfide dioxygenase-sulfurtransferase CstB | - |
| V5233_RS00360 (V5233_0000360) | - | 77829..78893 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| V5233_RS00365 (V5233_0000365) | cstR | 79029..79289 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| V5233_RS00370 (V5233_0000370) | - | 79289..79927 (+) | 639 | Protein_71 | sulfite exporter TauE/SafE family protein | - |
| V5233_RS00375 (V5233_0000375) | - | 80272..80934 (-) | 663 | WP_110417900.1 | class I SAM-dependent methyltransferase | - |
| V5233_RS00380 (V5233_0000380) | - | 81326..81385 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| V5233_RS00385 (V5233_0000385) | erm(A) | 81443..82174 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| V5233_RS00390 (V5233_0000390) | - | 82300..83082 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| V5233_RS00395 (V5233_0000395) | - | 83233..83610 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| V5233_RS00400 (V5233_0000400) | - | 83617..85509 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| V5233_RS00405 (V5233_0000405) | - | 85506..86591 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| V5233_RS00410 (V5233_0000410) | - | 86710..87027 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| V5233_RS00415 (V5233_0000415) | - | 87048..87554 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| V5233_RS00420 (V5233_0000420) | - | 87572..87883 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| V5233_RS00425 (V5233_0000425) | - | 87970..88320 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V5233_RS00430 (V5233_0000430) | ccrB | 88838..90466 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| V5233_RS00435 (V5233_0000435) | ccrA | 90488..91837 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=1011842 V5233_RS00430 WP_001186602.1 88838..90466(-) (ccrB) [Staphylococcus aureus strain BSN25]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=1011842 V5233_RS00430 WP_001186602.1 88838..90466(-) (ccrB) [Staphylococcus aureus strain BSN25]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |