Detailed information NTG1011689

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H1W94_RS07700
• Genome accession: NZ_LR822041
• Coordinates: 1475633..1476709 (-)
• Length: 358 a.a.
• NCBI ID: WP_011226464.1
• Uniprot ID: Q5M2Z4
• Organism: Streptococcus thermophilus isolate STH_CIRM_1122
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1470633..1481709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W94_RS07680 (STHERMO_1693)	-	1471745..1473811 (-)	2067	WP_011227498.1	cation:proton antiporter	-
H1W94_RS07685 (STHERMO_1694)	-	1473820..1474062 (-)	243	WP_011227499.1	hypothetical protein	-
H1W94_RS07690 (STHERMO_1695)	-	1474059..1474607 (-)	549	WP_004197152.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
H1W94_RS07695 (STHERMO_1696)	-	1474604..1475548 (-)	945	WP_011226463.1	TIGR01212 family radical SAM protein	-
H1W94_RS07700 (STHERMO_1697)	sepM	1475633..1476709 (-)	1077	WP_011226464.1	SepM family pheromone-processing serine protease	Regulator
H1W94_RS07705 (STHERMO_1698)	coaD	1476687..1477184 (-)	498	WP_011226465.1	pantetheine-phosphate adenylyltransferase	-
H1W94_RS07710 (STHERMO_1699)	rsmD	1477218..1477817 (-)	600	WP_011227500.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H1W94_RS07715 (STHERMO_1700)	trxB	1477908..1478861 (-)	954	WP_255136104.1	thioredoxin-disulfide reductase	-
H1W94_RS07720 (STHERMO_1701)	-	1478894..1479118 (-)	225	WP_011226468.1	DUF4059 family protein	-
H1W94_RS07725 (STHERMO_1702)	amiE	1479333..1480076 (-)	744	WP_011226469.1	amino acid ABC transporter ATP-binding protein	Regulator
H1W94_RS07730 (STHERMO_1703)	-	1480076..1480822 (-)	747	WP_095559509.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39232.11 Da
• Isoelectric Point: 9.4944

>NTDB_id=1011689 H1W94_RS07700 WP_011226464.1 1475633..1476709(-) (sepM) [Streptococcus thermophilus isolate STH_CIRM_1122]
MANKTKSKSLLEKMWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYTQFNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAVYQGLTLAGKEVSLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGAVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKADPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=1011689 H1W94_RS07700 WP_011226464.1 1475633..1476709(-) (sepM) [Streptococcus thermophilus isolate STH_CIRM_1122]
GTGGCAAACAAGACAAAATCTAAATCGCTATTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATACTCAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGCATCAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCTACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGCAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGATCAAGAGTCCTGAGAATGTTAAGTTTAAACTGGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATGTTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGGCTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGGACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATGA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (137-206)

3D structure

• AlphaFold DB: Q5M2Z4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.757	95.251	0.598