Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H1W94_RS06630 Genome accession   NZ_LR822041
Coordinates   1267685..1268329 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1122     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1262685..1273329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W94_RS06605 (STHERMO_1455) - 1264786..1265784 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  H1W94_RS06610 (STHERMO_1456) trmD 1265786..1266505 (-) 720 WP_011227401.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H1W94_RS06615 (STHERMO_1457) rimM 1266495..1267013 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  H1W94_RS06630 (STHERMO_1458) vraR 1267685..1268329 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  H1W94_RS06635 (STHERMO_1459) - 1268319..1269329 (-) 1011 WP_011227402.1 sensor histidine kinase -
  H1W94_RS06640 (STHERMO_1460) liaF 1269326..1270024 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W94_RS09870 (STHERMO_1461) - 1270290..1270445 (-) 156 WP_011226290.1 ion channel -
  H1W94_RS06650 (STHERMO_1464) stkP/pknB 1271082..1272953 (-) 1872 WP_011226292.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1011672 H1W94_RS06630 WP_002951384.1 1267685..1268329(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1122]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1011672 H1W94_RS06630 WP_002951384.1 1267685..1268329(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACTGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379