Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   H1W94_RS06265 Genome accession   NZ_LR822041
Coordinates   1189208..1189888 (-) Length   226 a.a.
NCBI ID   WP_011226224.1    Uniprot ID   Q5M3P0
Organism   Streptococcus thermophilus isolate STH_CIRM_1122     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1184208..1194888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W94_RS06235 (STHERMO_1365) - 1184417..1184866 (-) 450 WP_011227350.1 cytidine deaminase family protein -
  H1W94_RS06240 (STHERMO_1366) - 1184877..1185056 (-) 180 Protein_1165 ABC transporter permease -
  H1W94_RS06245 (STHERMO_1367) - 1185058..1185255 (-) 198 Protein_1166 YkgJ family cysteine cluster protein -
  H1W94_RS06250 (STHERMO_1368) - 1185340..1187340 (-) 2001 WP_156703443.1 ABC transporter permease -
  H1W94_RS06255 (STHERMO_1369) - 1187342..1188100 (-) 759 WP_011227353.1 ABC transporter ATP-binding protein -
  H1W94_RS06260 (STHERMO_1370) - 1188244..1189218 (-) 975 WP_011227354.1 sensor histidine kinase -
  H1W94_RS06265 (STHERMO_1371) braR 1189208..1189888 (-) 681 WP_011226224.1 response regulator transcription factor Regulator
  H1W94_RS06270 (STHERMO_1372) - 1190339..1190880 (+) 542 Protein_1171 xanthine phosphoribosyltransferase -
  H1W94_RS06275 - 1190880..1192152 (+) 1273 Protein_1172 nucleobase:cation symporter-2 family protein -
  H1W94_RS06280 (STHERMO_1376) - 1192280..1193629 (+) 1350 WP_059257415.1 MATE family efflux transporter -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 26100.45 Da        Isoelectric Point: 4.9992

>NTDB_id=1011671 H1W94_RS06265 WP_011226224.1 1189208..1189888(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_1122]
MHKILLVEDDEVIRQQVKKMLEQWGYEVVLVEDFMEVLSIFVKVEPHLVLMDIGLPLFNGYHWCQEIRKVSKVPIMFLSS
RDQAMDIVMAINMGGDDFVTKPFDQNVLLAKIQGLLRRSYEFGKDQNLLEYMGVILNLKAMDLVYQGEVVSLTKNEFQIL
QVLFDHAGNIVSREDLMKELWNSDFFIDDNTLSVNVARLRKKLEAVGLKDFIETKKGVGYGLRHDG

Nucleotide


Download         Length: 681 bp        

>NTDB_id=1011671 H1W94_RS06265 WP_011226224.1 1189208..1189888(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGCATAAGATTTTATTAGTTGAGGACGACGAGGTTATCCGTCAACAAGTCAAAAAAATGCTAGAACAGTGGGGTTACGA
AGTTGTTCTTGTTGAAGATTTCATGGAAGTATTATCTATTTTTGTAAAAGTAGAGCCCCACTTGGTTCTTATGGACATTG
GTTTACCTCTATTTAATGGTTATCATTGGTGTCAGGAAATTCGGAAGGTCTCCAAGGTGCCTATTATGTTCTTGTCTTCC
AGAGATCAGGCCATGGATATCGTTATGGCAATCAATATGGGTGGGGACGACTTTGTGACTAAACCCTTTGACCAAAATGT
TCTCTTGGCAAAAATTCAAGGGCTTTTGCGCCGATCTTATGAGTTTGGAAAGGATCAGAATCTTTTGGAATATATGGGTG
TGATTTTGAACCTTAAGGCCATGGATCTGGTTTATCAGGGAGAAGTCGTTTCTTTGACCAAGAACGAGTTTCAGATTTTA
CAAGTTCTCTTCGACCATGCTGGAAATATCGTTAGTCGGGAAGACCTCATGAAGGAGCTTTGGAATAGTGACTTCTTTAT
TGATGATAATACCCTGTCTGTCAATGTGGCACGTTTACGTAAGAAGTTAGAGGCTGTTGGTTTGAAGGACTTTATTGAAA
CCAAGAAAGGTGTCGGTTACGGGTTGCGTCATGATGGATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M3P0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

52.294

96.46

0.504
  micA Streptococcus pneumoniae Cp1015

35.043

100

0.363