Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLUC023_RS08365 Genome accession   NZ_CP158368
Coordinates   1643341..1644813 (-) Length   490 a.a.
NCBI ID   WP_021211938.1    Uniprot ID   -
Organism   Lactococcus cremoris strain UC023     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1638341..1649813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC023_RS08345 (LLUC023_08355) murG 1638654..1639727 (-) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  LLUC023_RS08350 (LLUC023_08360) murD 1639970..1641319 (-) 1350 WP_021211936.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLUC023_RS08355 (LLUC023_08365) - 1641488..1641829 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLUC023_RS08360 (LLUC023_08370) - 1641914..1643155 (-) 1242 WP_021211937.1 ammonium transporter -
  LLUC023_RS08365 (LLUC023_08375) covS 1643341..1644813 (-) 1473 WP_021211938.1 HAMP domain-containing histidine kinase Regulator
  LLUC023_RS08370 (LLUC023_08380) covR 1644826..1645518 (-) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLUC023_RS08375 (LLUC023_08385) - 1645674..1646204 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLUC023_RS08380 (LLUC023_08390) - 1646337..1646582 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLUC023_RS08385 (LLUC023_08395) - 1646906..1647268 (-) 363 Protein_1634 TIGR02328 family protein -
  LLUC023_RS08390 (LLUC023_08400) - 1647505..1648416 (-) 912 Protein_1635 CHAP domain-containing protein -
  LLUC023_RS08395 (LLUC023_08405) - 1648509..1649345 (-) 837 WP_031288631.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55891.76 Da        Isoelectric Point: 4.7018

>NTDB_id=1011010 LLUC023_RS08365 WP_021211938.1 1643341..1644813(-) (covS) [Lactococcus cremoris strain UC023]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=1011010 LLUC023_RS08365 WP_021211938.1 1643341..1644813(-) (covS) [Lactococcus cremoris strain UC023]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACGTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.694

100

0.947

Multiple sequence alignment