Detailed information NTG0101100

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: T303_RS07845
• Genome accession: NZ_CP006819
• Coordinates: 1479912..1480556 (-)
• Length: 214 a.a.
• NCBI ID: WP_002951384.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus ASCC 1275
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1474912..1485556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
T303_RS07820 (T303_07960)	-	1477013..1478011 (-)	999	WP_014608529.1	NAD(P)/FAD-dependent oxidoreductase	-
T303_RS07825 (T303_07965)	trmD	1478013..1478732 (-)	720	WP_024703937.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
T303_RS07830 (T303_07970)	rimM	1478722..1479240 (-)	519	WP_011226286.1	ribosome maturation factor RimM	-
T303_RS07845 (T303_07985)	vraR	1479912..1480556 (-)	645	WP_002951384.1	response regulator transcription factor	Regulator
T303_RS07850 (T303_07990)	-	1480546..1481556 (-)	1011	WP_011226288.1	sensor histidine kinase	-
T303_RS07855 (T303_07995)	liaF	1481553..1482251 (-)	699	WP_011226289.1	cell wall-active antibiotics response protein LiaF	-
T303_RS11690 (T303_08000)	-	1482506..1482673 (-)	168	WP_014608530.1	potassium channel family protein	-
T303_RS07860 (T303_08005)	stkP/pknB	1483311..1485182 (-)	1872	WP_024703938.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24048.39 Da
• Isoelectric Point: 4.5864

>NTDB_id=101100 T303_RS07845 WP_002951384.1 1479912..1480556(-) (vraR) [Streptococcus thermophilus ASCC 1275]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide

• Length: 645 bp

>NTDB_id=101100 T303_RS07845 WP_002951384.1 1479912..1480556(-) (vraR) [Streptococcus thermophilus ASCC 1275]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-118)

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	50.485	96.262	0.486
degU	Bacillus subtilis subsp. subtilis str. 168	36.161	100	0.379