Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H1W91_RS06835 Genome accession   NZ_LR822032
Coordinates   1308604..1309248 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1303604..1314248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS06810 (STHERMO_1494) - 1305706..1306704 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  H1W91_RS06815 (STHERMO_1495) trmD 1306706..1307425 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H1W91_RS06820 (STHERMO_1496) rimM 1307415..1307933 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  H1W91_RS06835 (STHERMO_1497) vraR 1308604..1309248 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  H1W91_RS06840 (STHERMO_1498) - 1309238..1310248 (-) 1011 WP_011226288.1 sensor histidine kinase -
  H1W91_RS06845 (STHERMO_1499) liaF 1310245..1310943 (-) 699 WP_180477088.1 cell wall-active antibiotics response protein LiaF -
  H1W91_RS10120 (STHERMO_1500) - 1311209..1311364 (-) 156 WP_232087096.1 ion channel -
  H1W91_RS06855 (STHERMO_1503) - 1312097..1313346 (+) 1250 Protein_1295 ISL3 family transposase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1010834 H1W91_RS06835 WP_002951384.1 1308604..1309248(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1050]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1010834 H1W91_RS06835 WP_002951384.1 1308604..1309248(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379