Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H1W74_RS08455 Genome accession   NZ_LR822031
Coordinates   1641910..1642203 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1636910..1647203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS08420 (STHERMO_1922) - 1637313..1637756 (-) 444 WP_002946118.1 hypothetical protein -
  H1W74_RS09935 (STHERMO_1923) - 1637830..1638255 (-) 426 WP_014608739.1 CPBP family intramembrane glutamic endopeptidase -
  H1W74_RS08430 (STHERMO_1925) - 1638498..1638695 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1W74_RS08435 (STHERMO_1926) - 1638944..1640137 (-) 1194 WP_022096898.1 acetate kinase -
  H1W74_RS08440 (STHERMO_1927) comGH 1640193..1641149 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H1W74_RS08445 (STHERMO_1928) comGG 1641194..1641511 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  H1W74_RS08450 (STHERMO_1929) comGF 1641489..1641926 (-) 438 WP_022096897.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W74_RS08455 (STHERMO_1930) comGE 1641910..1642203 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1W74_RS08460 (STHERMO_1931) comGD 1642175..1642603 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W74_RS08465 (STHERMO_1932) comGC 1642563..1642889 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W74_RS08470 (STHERMO_1933) comGB 1642886..1643986 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W74_RS08475 (STHERMO_1934) comGA/cglA/cilD 1643868..1644809 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W74_RS08480 (STHERMO_1935) - 1644890..1645252 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=1010762 H1W74_RS08455 WP_011226625.1 1641910..1642203(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1047]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1010762 H1W74_RS08455 WP_011226625.1 1641910..1642203(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1047]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361

Multiple sequence alignment