Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H1W74_RS06415 Genome accession   NZ_LR822031
Coordinates   1246650..1247294 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1241650..1252294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS06390 (STHERMO_1458) - 1243751..1244749 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  H1W74_RS06395 (STHERMO_1459) trmD 1244751..1245470 (-) 720 WP_002951382.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H1W74_RS06400 (STHERMO_1460) rimM 1245460..1245978 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  H1W74_RS06415 (STHERMO_1461) vraR 1246650..1247294 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  H1W74_RS06420 (STHERMO_1462) - 1247284..1248294 (-) 1011 WP_011226288.1 sensor histidine kinase -
  H1W74_RS06425 (STHERMO_1463) liaF 1248291..1248989 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W74_RS09815 (STHERMO_1464) - 1249244..1249411 (-) 168 WP_232089277.1 ion channel -
  H1W74_RS06435 (STHERMO_1467) stkP/pknB 1250048..1251919 (-) 1872 WP_002946880.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1010728 H1W74_RS06415 WP_002951384.1 1246650..1247294(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1047]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1010728 H1W74_RS06415 WP_002951384.1 1246650..1247294(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTAGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379