Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H1W89_RS03005 Genome accession   NZ_LR822029
Coordinates   563942..564586 (+) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 558942..569586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W89_RS02985 (STHERMO_0627) stkP/pknB 559317..561188 (+) 1872 WP_084831154.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H1W89_RS09735 (STHERMO_0630) - 561825..561992 (+) 168 WP_014608530.1 potassium channel family protein -
  H1W89_RS02995 (STHERMO_0631) liaF 562247..562945 (+) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W89_RS03000 (STHERMO_0632) - 562942..563952 (+) 1011 WP_180474517.1 sensor histidine kinase -
  H1W89_RS03005 (STHERMO_0633) vraR 563942..564586 (+) 645 WP_002951384.1 response regulator transcription factor Regulator
  H1W89_RS03020 (STHERMO_0635) rimM 565258..565776 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  H1W89_RS03025 (STHERMO_0636) trmD 565766..566485 (+) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H1W89_RS03030 (STHERMO_0637) - 566487..567485 (+) 999 WP_014608529.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1010500 H1W89_RS03005 WP_002951384.1 563942..564586(+) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1035]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1010500 H1W89_RS03005 WP_002951384.1 563942..564586(+) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1035]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379