Detailed information NTG1010429

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: H1X63_RS07940
• Genome accession: NZ_LR822027
• Coordinates: 1533634..1535733 (-)
• Length: 699 a.a.
• NCBI ID: WP_180487738.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1528634..1540733

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS07910 (STHERMO_1723)	pptB	1529101..1530135 (-)	1035	WP_415669366.1	ABC transporter permease	Regulator
H1X63_RS07915 (STHERMO_1724)	pptA	1530135..1530866 (-)	732	WP_179972197.1	ABC transporter ATP-binding protein	Regulator
H1X63_RS07920 (STHERMO_1725)	-	1530931..1531350 (+)	420	WP_179972198.1	HIT family protein	-
H1X63_RS07925 (STHERMO_1726)	-	1531347..1531646 (+)	300	WP_180487736.1	hypothetical protein	-
H1X63_RS07930 (STHERMO_1727)	-	1531698..1532426 (-)	729	WP_180482416.1	hypothetical protein	-
H1X63_RS07935 (STHERMO_1728)	-	1532445..1533080 (-)	636	WP_180487737.1	DUF4230 domain-containing protein	-
H1X63_RS11040	-	1533099..1533224 (-)	126	WP_260215148.1	hypothetical protein	-
H1X63_RS07940 (STHERMO_1729)	clpE	1533634..1535733 (-)	2100	WP_180487738.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H1X63_RS07945 (STHERMO_1730)	-	1536447..1537538 (-)	1092	WP_180487739.1	nucleotidyltransferase	-
H1X63_RS07950 (STHERMO_1731)	-	1537545..1538285 (-)	741	WP_277426406.1	class I SAM-dependent DNA methyltransferase	-
H1X63_RS07955 (STHERMO_1732)	rsfS	1538610..1538963 (-)	354	WP_011227491.1	ribosome silencing factor	-
H1X63_RS07960 (STHERMO_1733)	yqeK	1538987..1539577 (-)	591	WP_084829055.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
H1X63_RS07965 (STHERMO_1734)	-	1539574..1540206 (-)	633	WP_065972527.1	nicotinate-nucleotide adenylyltransferase	-
H1X63_RS07970 (STHERMO_1735)	yhbY	1540311..1540628 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77245.14 Da
• Isoelectric Point: 4.7997

>NTDB_id=1010429 H1X63_RS07940 WP_180487738.1 1533634..1535733(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_998]
MNNNFNNMDDLFDQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVTRSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=1010429 H1X63_RS07940 WP_180487738.1 1533634..1535733(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCGATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTTGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGTAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGACACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (255-349)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.924	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae TIGR4	48.499	90.558	0.439
clpE	Streptococcus pneumoniae R6	48.499	90.558	0.439
clpE	Streptococcus pneumoniae D39	48.499	90.558	0.439
clpE	Streptococcus pneumoniae Rx1	48.499	90.558	0.439
clpC	Bacillus subtilis subsp. subtilis str. 168	45.975	92.418	0.425
clpC	Streptococcus thermophilus LMD-9	43.417	91.273	0.396
clpC	Streptococcus thermophilus LMG 18311	43.26	91.273	0.395
clpC	Streptococcus pneumoniae TIGR4	43.66	89.127	0.389
clpC	Streptococcus pneumoniae Rx1	43.66	89.127	0.389
clpC	Streptococcus pneumoniae D39	43.66	89.127	0.389
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.436	88.269	0.383
clpC	Streptococcus mutans UA159	43.156	88.841	0.383