Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   H1X63_RS06525 Genome accession   NZ_LR822027
Coordinates   1243635..1244315 (-) Length   226 a.a.
NCBI ID   WP_179972041.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1238635..1249315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS06495 (STHERMO_1404) - 1238843..1239292 (-) 450 WP_179972037.1 cytidine deaminase family protein -
  H1X63_RS06500 (STHERMO_1405) - 1239303..1239482 (-) 180 Protein_1221 ABC transporter permease -
  H1X63_RS06505 (STHERMO_1406) - 1239484..1239681 (-) 198 Protein_1222 YkgJ family cysteine cluster protein -
  H1X63_RS06510 (STHERMO_1407) - 1239766..1241766 (-) 2001 WP_179972039.1 ABC transporter permease -
  H1X63_RS06515 (STHERMO_1408) - 1241768..1242526 (-) 759 WP_179972040.1 ABC transporter ATP-binding protein -
  H1X63_RS06520 (STHERMO_1409) - 1242671..1243645 (-) 975 WP_179973018.1 sensor histidine kinase -
  H1X63_RS06525 (STHERMO_1410) braR 1243635..1244315 (-) 681 WP_179972041.1 response regulator transcription factor Regulator
  H1X63_RS06530 (STHERMO_1411) - 1244759..1245339 (+) 581 Protein_1227 xanthine phosphoribosyltransferase -
  H1X63_RS06535 - 1245339..1246617 (+) 1279 Protein_1228 nucleobase:cation symporter-2 family protein -
  H1X63_RS06540 (STHERMO_1415) - 1246745..1248094 (+) 1350 WP_014621757.1 MATE family efflux transporter -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 26146.54 Da        Isoelectric Point: 5.0048

>NTDB_id=1010413 H1X63_RS06525 WP_179972041.1 1243635..1244315(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_998]
MHKILLVEDDEVIRQQVKKMLEQWGYEVVLVEDFMEVLSIFVKVEPHLVLMDIGLPLFNGYHWCQEIRKVSKVPIMFLSS
RDQAMDIVMAINMGGDDFMTKPFDQNVLLAKIQGLLRRSYEFGKDQNLLEYMGVILNLKAMDLVYQGEVVSLTKNEFQIL
QVLFEHAGNIVSREDLMKELWNSDFFIDDNTLSVNVARLRKKLEAVGLKDFIETKKGVGYGLRHDG

Nucleotide


Download         Length: 681 bp        

>NTDB_id=1010413 H1X63_RS06525 WP_179972041.1 1243635..1244315(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGCATAAGATTTTATTAGTGGAGGACGACGAGGTTATCCGTCAACAAGTCAAAAAAATGCTAGAACAATGGGGTTACGA
AGTTGTTCTTGTTGAAGATTTCATGGAAGTATTATCTATTTTTGTAAAAGTAGAGCCCCACTTGGTTCTTATGGACATTG
GTTTACCTCTATTTAATGGTTATCATTGGTGTCAGGAAATTCGTAAGGTCTCCAAGGTGCCTATTATGTTCTTGTCTTCC
AGAGATCAGGCCATGGATATCGTTATGGCAATCAATATGGGTGGGGACGACTTTATGACTAAACCCTTTGACCAAAATGT
TCTCTTGGCAAAAATTCAAGGGCTTTTGCGCCGATCTTATGAGTTTGGAAAGGATCAGAATCTTTTGGAATATATGGGTG
TGATTTTGAACCTTAAGGCCATGGATCTGGTTTATCAGGGAGAAGTCGTTTCTTTGACCAAGAACGAGTTTCAGATTTTA
CAAGTTCTCTTCGAACATGCTGGTAATATCGTTAGTCGGGAAGACCTCATGAAGGAGCTTTGGAATAGTGACTTCTTTAT
TGATGATAATACCCTGTCTGTCAATGTGGCACGTTTACGTAAGAAGTTAGAGGCAGTTGGTTTGAAGGACTTTATTGAAA
CCAAGAAAGGTGTCGGTTACGGGTTGCGTCATGATGGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

52.294

96.46

0.504

Multiple sequence alignment