Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H0514_RS03135 Genome accession   NZ_LR822020
Coordinates   602293..602937 (+) Length   214 a.a.
NCBI ID   WP_022496266.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 597293..607937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS03120 (STHERMO_0697) stkP/pknB 597671..599542 (+) 1872 WP_179972076.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H0514_RS03125 (STHERMO_0701) liaF 600598..601296 (+) 699 WP_179972075.1 cell wall-active antibiotics response protein LiaF -
  H0514_RS03130 (STHERMO_0702) - 601293..602303 (+) 1011 WP_011227402.1 sensor histidine kinase -
  H0514_RS03135 (STHERMO_0703) vraR 602293..602937 (+) 645 WP_022496266.1 response regulator transcription factor Regulator
  H0514_RS03150 (STHERMO_0705) rimM 603614..604132 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  H0514_RS03155 (STHERMO_0706) trmD 604122..604841 (+) 720 WP_179972074.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H0514_RS03160 (STHERMO_0707) - 604843..605841 (+) 999 WP_179972073.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23991.33 Da        Isoelectric Point: 4.5814

>NTDB_id=1009958 H0514_RS03135 WP_022496266.1 602293..602937(+) (vraR) [Streptococcus thermophilus isolate STH_CIRM_956]
MSNKINVILVDDHEMVRLGLKSFLNLQGDIEVVGEAGNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1009958 H0514_RS03135 WP_022496266.1 602293..602937(+) (vraR) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGTCGAATAAGATTAATGTGATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGACTTAAGAGTTTCTTGAATCTCCA
AGGAGATATAGAAGTGGTTGGAGAGGCAGGAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCCGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGGACTTACATGATGACTTGACTGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.971

96.262

0.491
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379