Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   H0506_RS06135 Genome accession   NZ_LR822015
Coordinates   1173505..1174185 (-) Length   226 a.a.
NCBI ID   WP_011226224.1    Uniprot ID   Q5M3P0
Organism   Streptococcus thermophilus isolate STH_CIRM_65     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1168505..1179185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0506_RS06105 (STHERMO_1347) - 1168713..1169162 (-) 450 WP_011226219.1 cytidine deaminase -
  H0506_RS06110 (STHERMO_1348) - 1169173..1169352 (-) 180 Protein_1143 ABC transporter permease -
  H0506_RS06115 (STHERMO_1349) - 1169354..1169551 (-) 198 Protein_1144 YkgJ family cysteine cluster protein -
  H0506_RS06120 (STHERMO_1350) - 1169636..1171636 (-) 2001 WP_011226221.1 ABC transporter permease -
  H0506_RS06125 (STHERMO_1351) - 1171638..1172396 (-) 759 WP_011226222.1 ABC transporter ATP-binding protein -
  H0506_RS06130 (STHERMO_1352) - 1172541..1173515 (-) 975 WP_011226223.1 sensor histidine kinase -
  H0506_RS06135 (STHERMO_1353) braR 1173505..1174185 (-) 681 WP_011226224.1 response regulator transcription factor Regulator
  H0506_RS06140 - 1174636..1175217 (+) 582 Protein_1149 xanthine phosphoribosyltransferase -
  H0506_RS06145 (STHERMO_1357) - 1175217..1176486 (+) 1270 Protein_1150 nucleobase:cation symporter-2 family protein -
  H0506_RS06150 (STHERMO_1358) - 1176614..1177963 (+) 1350 WP_087010026.1 MATE family efflux transporter -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 26100.45 Da        Isoelectric Point: 4.9992

>NTDB_id=1009657 H0506_RS06135 WP_011226224.1 1173505..1174185(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_65]
MHKILLVEDDEVIRQQVKKMLEQWGYEVVLVEDFMEVLSIFVKVEPHLVLMDIGLPLFNGYHWCQEIRKVSKVPIMFLSS
RDQAMDIVMAINMGGDDFVTKPFDQNVLLAKIQGLLRRSYEFGKDQNLLEYMGVILNLKAMDLVYQGEVVSLTKNEFQIL
QVLFDHAGNIVSREDLMKELWNSDFFIDDNTLSVNVARLRKKLEAVGLKDFIETKKGVGYGLRHDG

Nucleotide


Download         Length: 681 bp        

>NTDB_id=1009657 H0506_RS06135 WP_011226224.1 1173505..1174185(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_65]
ATGCATAAGATTTTATTAGTTGAGGACGACGAGGTTATCCGTCAACAAGTCAAAAAAATGCTAGAACAGTGGGGTTACGA
AGTTGTTCTTGTTGAAGATTTCATGGAAGTATTATCTATTTTTGTAAAAGTAGAGCCCCACTTGGTTCTTATGGACATTG
GTTTACCTCTATTTAATGGTTATCATTGGTGTCAGGAAATTCGTAAGGTCTCCAAGGTGCCTATTATGTTCTTGTCTTCC
AGAGATCAGGCCATGGATATCGTTATGGCAATCAATATGGGTGGGGACGACTTTGTGACTAAACCCTTTGACCAAAATGT
TCTCTTGGCAAAAATTCAAGGGCTTTTGCGCCGATCTTATGAGTTTGGAAAGGATCAGAATCTTTTGGAATATATGGGTG
TGATTTTGAACCTTAAGGCCATGGATCTGGTTTATCAGGGAGAAGTCGTTTCTTTGACTAAGAACGAGTTTCAGATTTTA
CAAGTTCTCTTCGACCATGCTGGAAATATCGTTAGTCGGGAAGACCTCATGAAGGAGCTTTGGAACAGTGACTTCTTTAT
TGATGATAATACCCTGTCTGTCAATGTGGCACGTTTACGTAAGAAGTTAGAGGCTGTTGGTTTGAAGGACTTTATTGAAA
CCAAGAAAGGTGTCGGTTACGGGTTGCGTCATGATGGATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M3P0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

52.294

96.46

0.504
  micA Streptococcus pneumoniae Cp1015

35.043

100

0.363

Multiple sequence alignment