Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HV361_RS10530 Genome accession   NZ_LR782232
Coordinates   2221686..2222342 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli isolate SC467     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2216686..2227342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HV361_RS10500 dcyD 2217566..2218552 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HV361_RS10505 tcyL 2218567..2219235 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HV361_RS10510 tcyN 2219232..2219984 (+) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HV361_RS10515 sdiA 2220214..2220936 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  HV361_RS10520 yecF 2221003..2221227 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HV361_RS10525 yecU 2221214..2221390 (-) 177 WP_000590347.1 protein YecU -
  HV361_RS22730 - 2221473..2221544 (-) 72 Protein_2062 transcriptional regulator -
  HV361_RS10530 letA 2221686..2222342 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HV361_RS10535 uvrC 2222339..2224171 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HV361_RS10540 pgsA 2224228..2224776 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HV361_RS10560 yecA 2225426..2226091 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=1008759 HV361_RS10530 WP_000611335.1 2221686..2222342(+) (letA) [Escherichia coli isolate SC467]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1008759 HV361_RS10530 WP_000611335.1 2221686..2222342(+) (letA) [Escherichia coli isolate SC467]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486