Detailed information NTG1008267

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: UXR36_RS07945
• Genome accession: NZ_CP157773
• Coordinates: 1639424..1641625 (-)
• Length: 733 a.a.
• NCBI ID: WP_001622275.1
• Uniprot ID: A0A0U1MM33
• Organism: Staphylococcus aureus strain BSN89
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1634424..1646625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR36_RS07930 (UXR36_007930)	lepA	1635928..1637751 (-)	1824	WP_000368338.1	translation elongation factor 4	-
UXR36_RS07935 (UXR36_007935)	rpsT	1638097..1638348 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
UXR36_RS07940 (UXR36_007940)	holA	1638393..1639367 (-)	975	WP_001282573.1	DNA polymerase III subunit delta	-
UXR36_RS07945 (UXR36_007945)	comEC	1639424..1641625 (-)	2202	WP_001622275.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
UXR36_RS07950 (UXR36_007950)	-	1641630..1642091 (-)	462	WP_182054836.1	ComE operon protein 2	-
UXR36_RS07955 (UXR36_007955)	comEA	1642183..1642869 (-)	687	WP_072468915.1	ComEA family DNA-binding protein	Machinery gene
UXR36_RS07960 (UXR36_007960)	-	1642909..1643625 (-)	717	WP_000084840.1	class I SAM-dependent methyltransferase	-
UXR36_RS07965 (UXR36_007965)	rsfS	1643628..1643981 (-)	354	WP_001088020.1	ribosome silencing factor	-
UXR36_RS07970 (UXR36_007970)	yqeK	1643982..1644566 (-)	585	WP_001017837.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
UXR36_RS07975 (UXR36_007975)	nadD	1644556..1645125 (-)	570	WP_000725165.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
UXR36_RS07980 (UXR36_007980)	yhbY	1645128..1645418 (-)	291	WP_000955234.1	ribosome assembly RNA-binding protein YhbY	-
UXR36_RS07985 (UXR36_007985)	aroE	1645422..1646228 (-)	807	WP_000666750.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 85048.20 Da
• Isoelectric Point: 10.0564

>NTDB_id=1008267 UXR36_RS07945 WP_001622275.1 1639424..1641625(-) (comEC) [Staphylococcus aureus strain BSN89]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVLLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITLPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVFDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNEYLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYRNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=1008267 UXR36_RS07945 WP_001622275.1 1639424..1641625(-) (comEC) [Staphylococcus aureus strain BSN89]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTACTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGATTAAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAAATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAAATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTATTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAACTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CGCTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTGCTTTTCCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACTTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGCTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGACAAGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTATTGATTGATACAGGTGGGAAAGTGTTTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGTTAAATGAAAGAGGGATAAATGAATTAGAGTACCTAATTTTAACACATC
CACACAATGACCATATTGGCGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAAGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTACAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATATTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGGAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATAGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

• Competence protein (Competence) (183-441)

3D structure

• AlphaFold DB: A0A0U1MM33

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.636	100	0.986
comEC	Staphylococcus aureus MW2	98.499	100	0.985