Detailed information NTG1007482

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ABKJ27_RS07945
• Genome accession: NZ_CP157578
• Coordinates: 1646950..1647987 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727281.1
• Uniprot ID: F9HAB0
• Organism: Streptococcus sp. KHUD_011
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1641950..1652987

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKJ27_RS07920 (ABKJ27_07930)	-	1642713..1644044 (-)	1332	WP_410011646.1	hemolysin family protein	-
ABKJ27_RS07925 (ABKJ27_07935)	endA	1644312..1645136 (-)	825	WP_410011647.1	DNA-entry nuclease EndA	Machinery gene
ABKJ27_RS07930 (ABKJ27_07940)	-	1645175..1645363 (-)	189	WP_004241151.1	DNA-directed RNA polymerase subunit beta	-
ABKJ27_RS07935 (ABKJ27_07945)	murA	1645356..1646639 (-)	1284	WP_410011648.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ABKJ27_RS07940 (ABKJ27_07950)	-	1646663..1646893 (-)	231	WP_004255861.1	DUF1146 family protein	-
ABKJ27_RS07945 (ABKJ27_07955)	sepM	1646950..1647987 (-)	1038	WP_000727281.1	SepM family pheromone-processing serine protease	Regulator
ABKJ27_RS07950 (ABKJ27_07960)	coaD	1647971..1648459 (-)	489	WP_410011649.1	pantetheine-phosphate adenylyltransferase	-
ABKJ27_RS07955 (ABKJ27_07965)	rsmD	1648449..1648988 (-)	540	WP_020902000.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ABKJ27_RS07960 (ABKJ27_07970)	asnA	1649053..1650045 (-)	993	WP_045612763.1	aspartate--ammonia ligase	-
ABKJ27_RS07965 (ABKJ27_07975)	-	1650157..1650840 (-)	684	WP_020901998.1	Bax inhibitor-1 family protein	-
ABKJ27_RS07970 (ABKJ27_07980)	-	1650895..1651635 (-)	741	WP_031237686.1	TrmH family RNA methyltransferase	-
ABKJ27_RS07975 (ABKJ27_07985)	-	1651669..1651947 (+)	279	WP_020901996.1	acylphosphatase	-
ABKJ27_RS07980 (ABKJ27_07990)	yidC	1652025..1652951 (+)	927	WP_020901995.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.57 Da
• Isoelectric Point: 4.8665

>NTDB_id=1007482 ABKJ27_RS07945 WP_000727281.1 1646950..1647987(-) (sepM) [Streptococcus sp. KHUD_011]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVNSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIADPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASAREGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1007482 ABKJ27_RS07945 WP_000727281.1 1646950..1647987(-) (sepM) [Streptococcus sp. KHUD_011]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCGTTTGTAGTGCCCTTGCC
CTATTATATAGAGGTTCCAGGCGGTTCAGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTCCAGCATGCCACTTTAGCTCATATGATTTATGCATGGTTGACGCCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGGATCAATCAATTCTACATGCAAAC
ATCGCAAAACATGGCCAAGTATCAAGGGCTAAAAACAGCTGGTAAAGATATCGAACTCAAATATCTTGGGGTTTATGTTT
TGACTGTGACGGATAATTCGACCTTTAAAGGGATTCTTAACATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGATTTGATTGATTACGTCAATTCTCAAAAACTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGTAAGATTATCACCTTGGAAAATGGCAAAAATGGGATTGGAATCGGTTTGATTGACCGTA
CGGAAGTGACCAGTGATGTCCCAATTCGCTTTTCAACAGCCGGTATCGGGGGTCCAAGTGCAGGACTCATGTTTAGTCTG
GCCATCTATACCCAAATAGCTGACCCTGGTCTTCGTAATGGTCGTATCGTTGCCGGTACAGGAACCATTGACCGCGATGG
TAATGTAGGGGACATTGGAGGTATTGATAAAAAAGTTGTAGCTTCGGCTAGAGAAGGTGCCGCGATTTTCTTTGCCCCAG
ATAACCCTGTTAGTGAAGAAGAACAAAAAGCGCATCCGGATGCGAAAAACAACTACCAAACAGCCCTAGAAGCAGCCAAA
ACAATCAAGACTGATATGAAAATCGTGCCAGTTAAAACCCTACAAGATGCAATTGATTACTTGAAAAACAATCCCTAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

3D structure

• AlphaFold DB: F9HAB0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591