Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ABKJ27_RS01775 Genome accession   NZ_CP157578
Coordinates   362688..363377 (+) Length   229 a.a.
NCBI ID   WP_033686437.1    Uniprot ID   A0A387AVS9
Organism   Streptococcus sp. KHUD_011     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 357688..368377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS01750 (ABKJ27_01760) gpsB 357781..358110 (+) 330 WP_000146534.1 cell division regulator GpsB -
  ABKJ27_RS01760 (ABKJ27_01770) - 358597..359754 (+) 1158 WP_020903409.1 class I SAM-dependent RNA methyltransferase -
  ABKJ27_RS01765 (ABKJ27_01775) - 359767..361176 (+) 1410 WP_020903408.1 cell division site-positioning protein MapZ family protein -
  ABKJ27_RS01770 (ABKJ27_01780) gndA 361252..362676 (+) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  ABKJ27_RS01775 (ABKJ27_01785) covR 362688..363377 (+) 690 WP_033686437.1 DNA-binding response regulator Regulator
  ABKJ27_RS01780 (ABKJ27_01790) mvk 363593..364471 (+) 879 WP_410011911.1 mevalonate kinase -
  ABKJ27_RS01785 (ABKJ27_01795) mvaD 364453..365406 (+) 954 WP_410011912.1 diphosphomevalonate decarboxylase -
  ABKJ27_RS01790 (ABKJ27_01800) - 365393..366400 (+) 1008 WP_261150145.1 phosphomevalonate kinase -
  ABKJ27_RS01795 (ABKJ27_01805) fni 366384..367394 (+) 1011 WP_261150143.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ABKJ27_RS01800 (ABKJ27_01810) liaF 367471..368169 (+) 699 WP_261150142.1 cell wall-active antibiotics response protein LiaF -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26785.91 Da        Isoelectric Point: 8.0259

>NTDB_id=1007443 ABKJ27_RS01775 WP_033686437.1 362688..363377(+) (covR) [Streptococcus sp. KHUD_011]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1007443 ABKJ27_RS01775 WP_033686437.1 362688..363377(+) (covR) [Streptococcus sp. KHUD_011]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGCCAGCCTCAGTGATTATGGTCTTG
GACCATCGCGAAGAATTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCGGTTATTAT
TGACAATCTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTAGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGTAATCTGCGTATGGATGTAGAGCATCATACCGTTTATCGTGGCGAGGAAATGATTGCTCTGACTCGT
CGTGAGTATGACCTTTTGGCCACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACCAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGTTACATTAAAACCGTTCGTGGTGTCGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387AVS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment