Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ABLU27_RS12130 Genome accession   NZ_CP157500
Coordinates   2344940..2346415 (-) Length   491 a.a.
NCBI ID   WP_406834513.1    Uniprot ID   -
Organism   Lactococcus lactis strain 2B-9     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2339940..2351415
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABLU27_RS12115 (ABLU27_12100) murD 2341199..2342551 (-) 1353 WP_003130748.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  ABLU27_RS12120 (ABLU27_12105) - 2343043..2343384 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  ABLU27_RS12125 (ABLU27_12110) - 2343516..2344757 (-) 1242 WP_058212572.1 ammonium transporter -
  ABLU27_RS12130 (ABLU27_12115) covS 2344940..2346415 (-) 1476 WP_406834513.1 ATP-binding protein Regulator
  ABLU27_RS12135 (ABLU27_12120) covR 2346424..2347116 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  ABLU27_RS12140 (ABLU27_12125) - 2347272..2347802 (-) 531 WP_058212571.1 DUF177 domain-containing protein -
  ABLU27_RS12145 (ABLU27_12130) - 2347933..2348178 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  ABLU27_RS12150 (ABLU27_12135) - 2348334..2348798 (-) 465 WP_058212570.1 hypothetical protein -
  ABLU27_RS12155 (ABLU27_12140) - 2348880..2349242 (-) 363 WP_010906050.1 TIGR02328 family protein -
  ABLU27_RS12160 (ABLU27_12145) - 2349727..2350224 (-) 498 WP_406834514.1 CHAP domain-containing protein -
  ABLU27_RS12165 (ABLU27_12150) - 2350318..2351154 (-) 837 WP_023164354.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56223.14 Da        Isoelectric Point: 4.8756

>NTDB_id=1007304 ABLU27_RS12130 WP_406834513.1 2344940..2346415(-) (covS) [Lactococcus lactis strain 2B-9]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=1007304 ABLU27_RS12130 WP_406834513.1 2344940..2346415(-) (covS) [Lactococcus lactis strain 2B-9]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACGATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTCATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.796

100

0.998

Multiple sequence alignment