Detailed information NTG1007192

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: ABLU28_RS05255
• Genome accession: NZ_CP157495
• Coordinates: 1025086..1025787 (+)
• Length: 233 a.a.
• NCBI ID: WP_004255173.1
• Uniprot ID: S6FFV7
• Organism: Lactococcus lactis strain 2B-1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1020086..1030787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABLU28_RS05240 (ABLU28_05240)	-	1022481..1023389 (+)	909	WP_003130548.1	diacylglycerol kinase family protein	-
ABLU28_RS05245 (ABLU28_05245)	-	1023536..1024222 (+)	687	WP_004255158.1	amino acid ABC transporter permease	-
ABLU28_RS05250 (ABLU28_05250)	-	1024222..1024956 (+)	735	WP_004255171.1	amino acid ABC transporter ATP-binding protein	-
ABLU28_RS05255 (ABLU28_05255)	mecA	1025086..1025787 (+)	702	WP_004255173.1	adaptor protein MecA	Regulator
ABLU28_RS05260 (ABLU28_05260)	-	1025790..1027109 (+)	1320	WP_406840983.1	glycosyltransferase family 4 protein	-
ABLU28_RS05265 (ABLU28_05265)	sufC	1027296..1028066 (+)	771	WP_004255181.1	Fe-S cluster assembly ATPase SufC	-
ABLU28_RS05270 (ABLU28_05270)	sufD	1028201..1029460 (+)	1260	WP_394326235.1	Fe-S cluster assembly protein SufD	-
ABLU28_RS05275 (ABLU28_05275)	-	1029460..1030677 (+)	1218	WP_406834738.1	cysteine desulfurase	-

Sequence

Protein

• Length: 233 a.a.
• Molecular weight: 27077.46 Da
• Isoelectric Point: 4.1246

>NTDB_id=1007192 ABLU28_RS05255 WP_004255173.1 1025086..1025787(+) (mecA) [Lactococcus lactis strain 2B-1]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide

• Length: 702 bp

>NTDB_id=1007192 ABLU28_RS05255 WP_004255173.1 1025086..1025787(+) (mecA) [Lactococcus lactis strain 2B-1]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCAATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTCGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-230)

3D structure

• AlphaFold DB: S6FFV7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Lactococcus lactis subsp. lactis strain DGCC12653	99.571	100	0.996
mecA	Lactococcus lactis subsp. cremoris KW2	96.996	100	0.97